Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species, ATP …

J Zhang, J Song, D Wu, J Wang, W Dong - Medical Oncology, 2015 - Springer
Hesperetin, a flavonoid from citrus fruits, has been proved to possess biological activity on
various types of human cancers. However, few related studies on hepatocellular carcinoma …

Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro

J Lee, JH Kim - PloS one, 2016 - journals.plos.org
Pancreatic cancer is one of the most appalling cancers with a pessimistic prognosis. Despite
many therapies, there has been no improvement of survival rates. In this study, we assessed …

Genistein induced anticancer effects on pancreatic cancer cell lines involves mitochondrial apoptosis, G0/G1cell cycle arrest and regulation of STAT3 signalling …

Y Bi, M Min, W Shen, Y Liu - Phytomedicine, 2018 - Elsevier
Background Genistein is a natural flavonoid that has been reported to exhibit anticancer
effects against different types of cancers which include, but are not limited to, breast and oral …

The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts

TW Nam, CI Yoo, HT Kim, CH Kwon, JY Park… - Journal of bone and …, 2008 - Springer
The present study was undertaken to evaluate effects of quercetin, a major dietary flavonoid
occurring in foods of plant origin, on cell viability and migration of osteoblastic cells …

A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention

AY Chen, YC Chen - Food chemistry, 2013 - Elsevier
Kaempferol is a polyphenol antioxidant found in fruits and vegetables. Many studies have
described the beneficial effects of dietary kaempferol in reducing the risk of chronic …

Kaempferol promotes apoptosis while inhibiting cell proliferation via androgen‐dependent pathway and suppressing vasculogenic mimicry and invasion in prostate …

J Da, M Xu, Y Wang, W Li, M Lu… - Analytical Cellular …, 2019 - Wiley Online Library
Kaempferol is a well‐known natural flavonol reported to be a potential treatment for multiple
cancers. In this study, we demonstrated that cell growth of androgen‐sensitive LNCaP cells …

Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL‐60 cancer cell xenograft growth in vivo

YC Hsiao, SF Peng, KC Lai, CL Liao… - Environmental …, 2019 - Wiley Online Library
Genistein, a major isoflavone compound in soybeans, has been shown to have biological
activities including anti‐cancer activates. In the present, we investigated the anti‐leukemia …

A natural flavonoid, apigenin isolated from Clerodendrum viscosum leaves, induces G2/M phase cell cycle arrest and apoptosis in MCF-7 cells through the regulation …

AK Shendge, D Chaudhuri, T Basu… - Clinical and Translational …, 2021 - Springer
Background With 9.6 million deaths in 2018, cancer remains the second leading cause of
death worldwide. Breast cancer is the most deadly type of cancer among females, with …

Kaempferol: A key emphasis to its anticancer potential

M Imran, B Salehi, J Sharifi-Rad, T Aslam Gondal… - Molecules, 2019 - mdpi.com
A marked decrease in human cancers, including breast cancer, bone cancer, and cervical
cancer, has been linked to the consumption of vegetable and fruit, and the corresponding …

Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway

X Yu, X Zhou, C Fu, Q Wang, T Nie… - Oncology …, 2015 - spandidos-publications.com
Celastrol is an active compound extracted from the root bark of Triptergium wilfordii Hook F.,
also known as ̔Thunder of God Vine̓. It is a well-known Chinese medicinal herb that was …