Obesity, adipokines and cancer: an update

CH Lee, YC Woo, Y Wang, CY Yeung… - Clinical …, 2015 - Wiley Online Library
Obesity causes dysfunction of adipose tissue, with resultant chronic inflammation and
adverse interplay of various adipokines, sex steroids and endocrine hormones. All these …

Obesity and cancer: the role of dysfunctional adipose tissue

RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …

Insights into the link between obesity and cancer

SE Ackerman, OA Blackburn, F Marchildon… - Current obesity …, 2017 - Springer
Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …

Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies

N Spyrou, KI Avgerinos, CS Mantzoros… - Current obesity …, 2018 - Springer
Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …

[HTML][HTML] Adipose tissue, obesity and adipokines: role in cancer promotion

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
Adipose tissue is a complex organ with endocrine, metabolic and immune regulatory roles.
Adipose depots have been characterized to release several adipocytokines that work locally …

The impact of obesity and adipokines on breast and gynecologic malignancies

S Tewari, R Vargas, O Reizes - … of the New York Academy of …, 2022 - Wiley Online Library
The link between obesity and multiple disease comorbidities is well established. In 2003,
Calle and colleagues presented the relationship between obesity and several cancer types …

A weighty problem: metabolic perturbations and the obesity-cancer link

CH O'Flanagan, LW Bowers… - … molecular biology and …, 2015 - degruyter.com
Obesity is an established risk factor for several cancers, including breast, colon, endometrial,
ovarian, gastric, pancreatic and liver, and is increasingly a public health concern. Obese …

Adipocytes: impact on tumor growth and potential sites for therapeutic intervention

S Hefetz-Sela, PE Scherer - Pharmacology & therapeutics, 2013 - Elsevier
The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …

Signals from the adipose microenvironment and the obesity–cancer link—a systematic review

C Himbert, M Delphan, D Scherer, LW Bowers… - Cancer prevention …, 2017 - AACR
Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

[PDF][PDF] Associations between adipokines and obesity-related cancer

G Paz-Filho, EL Lim, ML Wong, J Licinio - Front Biosci, 2011 - researchgate.net
[Frontiers in Bioscience 16, 1634-1650, January 1, 2011] 1634 Associations between
adipokines and obesity-related cancer Gilbert Page 1 [Frontiers in Bioscience 16, 1634-1650 …