Do bugs control our fate? The influence of the microbiome on autoimmunity

I Fung, JPD Garrett, A Shahane, M Kwan - Current allergy and asthma …, 2012 - Springer
Autoimmune disease has traditionally been thought to be due to the impact of environmental
factors on genetically susceptible individuals causing immune dysregulation and loss of …

The emerging world of microbiome in autoimmune disorders: Opportunities and challenges

AK Mangalam, M Yadav, R Yadav - Indian journal of …, 2021 - journals.lww.com
Trillions of commensal bacteria colonizing humans (microbiome) have emerged as essential
player (s) in human health. The alteration of the same has been linked with diseases …

Impact of helminth–microbiome interactions on childhood health and development—A clinical perspective

A Piazzesi, L Putignani - Parasite Immunology, 2023 - Wiley Online Library
Humans have co‐existed with parasites for virtually the entirety of our existence as a
species. Today, nearly one third of the human population is infected with at least one …

Intestinal microbiota: facts and fiction

M Kverka, H Tlaskalová-Hogenová - Digestive Diseases, 2017 - karger.com
In humans, the gut microbiota forms a complex ecosystem consisting of a vast number of
bacteria, Archaea, fungi and viruses. It represents a major stimulus to the development of the …

[HTML][HTML] Helminth infection and type 1 diabetes

P Zaccone, SW Hall - The review of diabetic studies: RDS, 2012 - ncbi.nlm.nih.gov
The increasing incidence of type 1 diabetes (T1D) and autoimmune diseases in
industrialized countries cannot be exclusively explained by genetic factors. Human …

Microbes, parasites and immune diseases

G Sorci, E Guivier, C Lippens, B Faivre - Evolutionary thinking in medicine …, 2016 - Springer
Post-industrial societies have witnessed a sharp increase in the incidence of many immune
diseases (eg inflammatory bowel disease, type-1 diabetes and allergies) during the last …

[HTML][HTML] Systemic impact of intestinal helminth infections

PK Mishra, M Palma, D Bleich, P Loke, WC Gause - Mucosal immunology, 2014 - Elsevier
In this review, we examine the evidence that intestinal helminths can control harmful
inflammatory responses and promote homeostasis by triggering systemic immune …

[HTML][HTML] Intestinal microbiota influences non-intestinal related autoimmune diseases

MC Opazo, EM Ortega-Rocha… - Frontiers in …, 2018 - frontiersin.org
The human body is colonized by millions of microorganisms named microbiota that interact
with our tissues in a cooperative and non-pathogenic manner. These microorganisms are …

The intestinal microbiome in spondyloarthritis

T Gill, M Asquith, JT Rosenbaum… - Current opinion in …, 2015 - journals.lww.com
We are beginning to appreciate the complex relationship between the gut microbiome and
host immune regulation and dysregulation in health and disease. Potentially important …

Helminth therapies: translating the unknown unknowns to known knowns

AR Khan, PG Fallon - International journal for parasitology, 2013 - Elsevier
The use of live helminth infections is currently in clinical trials as a novel approach for the
treatment of a range of allergic and autoimmune diseases. This rapid progression from …