Many individuals treated for depression suffer relapse or recurrence after treatment. Known
risk factors include number of previous depressive episodes and residual symptoms after …

OBJECTIVE: The recurrence of an affective disorder in people who initially recover from
major depressive disorder was characterized by using the unique longitudinal prospective …

BACKGROUND: Although antidepressants are conventionally given for 4–6weeks before
deciding on response, several reports suggest that early improvement predicts later …

BackgroundKnowledge of the risk of recurrence after recovery from major depressive
disorder (MDD) in the general population is scarce. MethodData were derived from 687 …

This report summarizes recommendations from the ACNP Task Force on the
conceptualization of remission and its implications for defining recovery, relapse …

BackgroundImprovement in depression within the first 2 weeks of antidepressant treatment
predicts good outcomes, but non-improvers can still respond or remit, whereas improvers …

BACKGROUND: The duration of untreated illness has been considered a likely predictor of
the course of psychotic disorders. However, there is only sparse data concerning the …

BackgroundAttainment of remission is viewed as the optimal outcome of acute
antidepressant treatment. However, some patients experience subsyndromal symptoms …

Objective The impact of subjective vs. objective illness severity on subjective cognitive
impairment in patients with depression has not been addressed. Methods This study is a …

Results: The risk ratio of responding to the adjunctive drug versus placebo was not
influenced by any of the study design factors analyzed (probability of receiving placebo, year …