Targeting GM-CSF in inflammatory diseases

IP Wicks, AW Roberts - Nature Reviews Rheumatology, 2016 - nature.com
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth factor first
identified as an inducer of differentiation and proliferation of granulocytes and macrophages …

[HTML][HTML] GM-CSF in inflammation

JA Hamilton - Journal of Experimental Medicine, 2020 - rupress.org
Granulocyte–macrophage colony-stimulating factor (GM-CSF) has many more functions
than its original in vitro identification as an inducer of granulocyte and macrophage …

Targeting GM-CSF in inflammatory and autoimmune disorders

AA Achuthan, KMC Lee, JA Hamilton - Seminars in immunology, 2021 - Elsevier
Granulocyte macrophage-colony stimulating factor (GM-CSF) was originally identified as a
growth factor for its ability to promote the proliferation and differentiation in vitro of bone …

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

AL Cornish, IK Campbell, BS McKenzie… - Nature Reviews …, 2009 - nature.com
Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-
stimulating factor (GM-CSF) are well-recognized regulators of hematopoiesis and have an …

GM-CSF: a promising target in inflammation and autoimmunity

KMC Lee, AA Achuthan, JA Hamilton - ImmunoTargets and therapy, 2020 - Taylor & Francis
The cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), was firstly
identified as being able to induce in vitro the proliferation and differentiation of bone marrow …

GM-CSF in inflammation and autoimmunity

JA Hamilton - Trends in immunology, 2002 - cell.com
Granulocyte macrophage-colony stimulating factor (GM-CSF) is now best viewed as a major
regulator governing the functions of granulocyte and macrophage lineage populations at all …

Roles of GM-CSF in the pathogenesis of autoimmune diseases: an update

N Lotfi, R Thome, N Rezaei, GX Zhang… - Frontiers in …, 2019 - frontiersin.org
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a
growth factor that induces the differentiation and proliferation of myeloid progenitors in the …

GM-CSF: from growth factor to central mediator of tissue inflammation

B Becher, S Tugues, M Greter - Immunity, 2016 - cell.com
The granulocyte-macrophage colony-stimulating factor (GM-CSF) was initially classified as a
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …

GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential

JA Hamilton - Expert review of clinical immunology, 2015 - Taylor & Francis
Granulocyte-macrophage colony-stimulating factor (GM-CSF) can be viewed as a pro-
inflammatory cytokine rather than as a key regulator of steady state and systemic …

Critical role for granulocyte colony-stimulating factor in inflammatory arthritis

KE Lawlor, IK Campbell, D Metcalf… - Proceedings of the …, 2004 - National Acad Sciences
Granulocyte colony-stimulating factor (G-CSF) is a well known regulator of granulopoiesis,
but the role of endogenous G-CSF in inflammatory joint disease has not been explored. We …