Depression is a major public health concern, and the period from late childhood through
early adolescence is a critical time in the development of depressive symptoms. In adults …

The prevalence of depression increases substantially during adolescence. Several
predictors of major depressive disorder have been established, but their predictive power is …

BackgroundReward processing deficits have been implicated in the etiology of depression.
A blunted reward positivity (RewP), an event-related potential elicited by feedback to …

Objective: A blunted neural response to rewards has recently emerged as a potential
mechanistic biomarker of adolescent depression. The reward positivity, an event-related …

Feedback negativity (FN) is an event-related potential elicited by monetary reward and loss;
it is thought to relate to reward-related neural activity and has been linked to depression in …

Blunted reward processing both characterizes major depressive disorder and predicts
increases in depressive symptoms. However, little is known about the interaction between …

Objective Adults and adolescents with major depressive disorder (MDD) show a blunted
neural response to rewards. Depression has been validated in children as young as age 3; …

Adolescence is a developmental period characterized by significant increases in the onset
of depression, but also by increases in depressive symptoms, even among psychiatrically …

Background Reduced reward responsiveness (RR) may contribute to depression
vulnerability. At the neurophysiological level, RR is reliably and validly assessed using the …

Background Research in adolescents and adults has suggested that altered neural
processing of reward following early life adversity is a highly promising depressive …