Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice

Z Shen, X Liang, CQ Rogers… - American Journal of …, 2010 - journals.physiology.org
The development of alcoholic fatty liver is associated with reduced adipocyte-derived
adiponectin levels, decreased hepatic adiponectin receptors, and deranged hepatic …

Adiponectin and alcoholic fatty liver disease

CQ Rogers, JM Ajmo, M You - IUBMB life, 2008 - Wiley Online Library
Worldwide, one of the most prevalent forms of chronic disease is alcoholic fatty liver, which
may progress to more severe forms of liver injury including steatohepatitis, fibrosis, and …

Adiponectin: a key adipokine in alcoholic fatty liver

M You, CQ Rogers - Experimental Biology and Medicine, 2009 - journals.sagepub.com
Alcoholic fatty liver is a major risk factor for advanced liver injuries such as steatohepatitis,
fibrosis, and cirrhosis. While the underlying mechanisms are multiple, the development of …

[PDF][PDF] Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice

M You, RV Considine, TC Leone, DP Kelly… - …, 2005 - Wiley Online Library
The protective effect of dietary saturated fatty acids against the development of alcoholic
liver disease has long been known, but the underlying mechanism is not completely …

Resveratrol alleviates alcoholic fatty liver in mice

JM Ajmo, X Liang, CQ Rogers… - American Journal of …, 2008 - journals.physiology.org
Alcoholic fatty liver is associated with inhibition of sirtuin 1 (SIRT1) and AMP-activated
kinase (AMPK), two critical signaling molecules regulating the pathways of hepatic lipid …

Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice

X Sun, Y Tang, X Tan, Q Li, W Zhong… - American Journal …, 2012 - journals.physiology.org
The development of alcohol-induced fatty liver is associated with a reduction of white
adipose tissue (WAT). Peroxisome proliferator-activated receptor (PPAR)-γ prominently …

The Adiponectin‐SIRT 1‐AMPK Pathway in Alcoholic Fatty Liver Disease in the Rat

ZA Jiang, JY Zhou, DF Zhou, ZT Zhu… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background Our previous work showed that binge drinking in the rat induced hepatic
steatosis which correlated with reduced expression of AMP‐activated protein kinase …

Chronic ethanol feeding to rats decreases adiponectin secretion by subcutaneous adipocytes

X Chen, BM Sebastian… - American Journal of …, 2007 - journals.physiology.org
Chronic ethanol feeding to mice and rats decreases serum adiponectin concentration and
adiponectin treatment attenuates chronic ethanol-induced liver injury. Although it is clear …

[HTML][HTML] Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone

X Sun, R Han, Z Wang, Y Chen - Diabetologia, 2006 - Springer
Aims/hypothesis Adiponectin is an adipocyte-derived hormone that plays a critical role in the
development of type 2 diabetes via interaction with adiponectin receptors 1 (ADIPOR1) and …

[PDF][PDF] Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

K Tomita, Y Oike, T Teratani, T Taguchi… - …, 2008 - Wiley Online Library
It is unclear how hepatic adiponectin resistance and sensitivity mediated by the adiponectin
receptor, AdipoR2, contributes to the progression of nonalcoholic steatohepatitis (NASH) …