Chemoenzymatic preparation of chondroitin sulfates with a defined sulfation pattern

E García-Junceda, A Bastida, E Doncel-Pérez… - 2016 - digital.csic.es
It is known that the proteoglycans present in the extracellular matrix, promote growth and
differentiation of neural cells during development and maturation of the central nervous …

[图书][B] Synthesis and biological activity of chondroitin sulfate biopolymers

SE Tully - 2007 - search.proquest.com
Chondroitin sulfate glycosaminoglycans are ubiquitously expressed linear, sulfated
polysaccharides involved in cell growth, neuronal development and spinal cord injury. The …

Synthesis of small molecules of chondroitin sulfate E and their biological studies on neurite outgrowth

S Liu - arabio.co.kr
Chondroitin sulfate glycosaminoglycans are sulfated, linear, heterogeneous
polysaccharides implicated in cell division, brain development and neuronal development …

Chondroitin-4-O-sulfatase from Bacteroides thetaiotaomicron: exploration of the substrate specificity

A Malleron, A Benjdia, O Berteau, C Le Narvor - Carbohydrate research, 2012 - Elsevier
Bacterial sulfatases can be good tools to increase the molecular diversity of
glycosaminoglycan synthetic fragments. A chondroitin 4-O-sulfatase from the human …

A chondroitin sulfate small molecule that stimulates neuronal growth

SE Tully, R Mabon, CI Gama, SM Tsai… - Journal of the …, 2004 - ACS Publications
Chondroitin sulfate glycosaminoglycans are sulfated polysaccharides involved in cell
division, neuronal development, and spinal cord injury. Here, we report the synthesis and …

Development of semisynthetic, regioselective pathways for accessing the missing sulfation patterns of chondroitin sulfate

G Vessella, S Traboni, D Cimini, A Iadonisi… - …, 2019 - ACS Publications
Chondroitin sulfate (CS) is a glycosaminoglycan playing several biological functions, which
seem to be encoded through its sulfation pattern. This “sulfation code” is still to be …

Specificity studies of bacterial sulfatases by means of structurally defined sulfated oligosaccharides isolated from shark cartilage chondroitin sulfate D

K Sugahara, T Kojima - European journal of biochemistry, 1996 - Wiley Online Library
Chondro‐4‐sulfatase and chondro‐6‐sulfatase from Proteus vulgaris and? 4hexuronate‐2‐
sulfatase from Flavobacteriurn heparinum are potentially useful tools for structural studies of …

Advances and challenges in biotechnological production of chondroitin sulfate and its oligosaccharides

W Zhang, R Xu, J Chen, H Xiong, Y Wang… - International journal of …, 2023 - Elsevier
Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …

Discrimination of sulfated isomers of chondroitin sulfate disaccharides by HILIC chromatography and on-line coupled tandem mass spectrometry

S Poyer, I Seffouh, C Lopin-Bon, JC Jacquinet… - 2021 - hal.science
Chondroitin sulfate (CS) are sulfated polysaccharides in particular present in the
extracellular matrix of the central nervous system. In this study, we developed a HILIC-MS …

Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides

J Li, G Su, J Liu - Angewandte Chemie International Edition, 2017 - Wiley Online Library
Chondroitin sulfate (CS) is a sulfated polysaccharide that plays essential physiological roles.
Here, we report an enzyme‐based method for the synthesis of a library of 15 different CS …