Interactions between proteins and glycosaminoglycans (GAGs) of the extracellular matrix
are important to the regulation of cellular processes including growth, differentiation and …

Over the last twenty years chondroitin sulfate (CS) has become a focus of interest of
neuroscience due to its indubitable role in shaping axonal growth, synaptic plasticity and …

Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays
essential roles in physiological processes. Here we report a facile approach to a library of …

Sulfated glycosaminoglycans (GAGs) are a class of important biologics that are currently
manufactured by extraction from animal tissues. Although such methods are unsustainable …

Sulfation of molecules in living organisms is a process that plays a key role in their
functionality. In mammals, the sulfation of polysaccharides (glycosaminoglycans) that form …

Our research integrates organic chemistry with neurobiology to explore molecular
mechanisms of neuronal communication in the brain. In particular, we are interested in …

Chondroitin sulfate and heparan sulfate proteoglycans are major components of the cell
surface and extracellular matrix in the brain. Both chondroitin sulfate and heparan sulfate …

The study of chondroitin sulfate (CS) and related proteoglycan (PG) structure and function
has significantly influenced our understanding of a wide variety of biological processes and …

Chondroitin sulfates are linear anionic sulfated polysaccharides found in biological tissues,
mainly within the extracellular matrix, which are degraded and altered by specific lyases …