Modular Synthesis of Heparan Sulfate Oligosaccharides Having N-Acetyl and N-Sulfate Moieties
Heparan sulfates are structurally diverse sulfated polysaccharides that reside at the surface
of all animal cells where they can interact with a multitude of proteins, thereby modulating a …
of all animal cells where they can interact with a multitude of proteins, thereby modulating a …
Chemical derivatization of sulfated glycosaminoglycans
E Bedini, A Laezza, A Iadonisi - European Journal of Organic …, 2016 - Wiley Online Library
Sulfated glycosaminoglycans (GAGs) are a family of complex polysaccharides ubiquitously
distributed in extracellular matrices and at cell surfaces and playing key roles in a myriad of …
distributed in extracellular matrices and at cell surfaces and playing key roles in a myriad of …
Sugar glues for broken neurons
H Vladimir, K Balagurunathan - 2013 - agris.fao.org
Proteoglycans (PGs) regulate diverse functions in the central nervous system (CNS) by
interacting with a number of growth factors, matrix proteins, and cell surface molecules …
interacting with a number of growth factors, matrix proteins, and cell surface molecules …
Chase‐ing regeneration: engineering chondroitinase for mammalian expression
GM Curinga, Y Jin, C Zhang, C Mashburn… - The FASEB …, 2009 - Wiley Online Library
Neurons fail to regenerate following spinal cord injury partly due to the up‐regulation of
chondroitin sulfate proteoglycans (CSPGs). Animal models of neuronal injury show …
chondroitin sulfate proteoglycans (CSPGs). Animal models of neuronal injury show …
Chemoenzymatic synthesis of glycosaminoglycans: re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains
Glycosaminoglycans (GAGs) are complex polysaccharides composed of hexosamine-
containing disaccharide repeating units. The three most studied classes of GAGs …
containing disaccharide repeating units. The three most studied classes of GAGs …
Targeting inhibitory chondroitin sulphate proteoglycans to promote plasticity after injury
Chondroitin sulphate proteoglycans (CSPGs) are one of the major families of inhibitory
extracellular matrix molecules in the central nervous system. The expression of various …
extracellular matrix molecules in the central nervous system. The expression of various …
Recombinant expression, purification, and kinetic characterization of chondroitinase AC and chondroitinase B from Flavobacterium heparinum
K Pojasek, Z Shriver, P Kiley, G Venkataraman… - Biochemical and …, 2001 - Elsevier
Glycosaminoglycans (GAGs) are a family of complex polysaccharides involved in a diversity
of biological processes, ranging from cell signaling to blood coagulation. Chondroitin sulfate …
of biological processes, ranging from cell signaling to blood coagulation. Chondroitin sulfate …
Production of chondroitin sulfate and chondroitin
C Schiraldi, D Cimini, M De Rosa - Applied microbiology and …, 2010 - Springer
The production of microbial polysaccharides has recently gained much interest because of
their potential biotechnological applications. Several pathogenic bacteria are known to …
their potential biotechnological applications. Several pathogenic bacteria are known to …
A highly active chondroitin sulfate lyase ABC for enzymatic depolymerization of chondroitin sulfate
XM Fan, JY Huang, XM Ling, W Wei, WB Su, YW Zhang - Polymers, 2022 - mdpi.com
Enzymatic preparation of low-molecular-weight chondroitin sulfate (LMWCS) has received
increasing attention. In this work, a chondroitin sulfate lyase ABC (Chon-ABC) was …
increasing attention. In this work, a chondroitin sulfate lyase ABC (Chon-ABC) was …
[引用][C] 4-O-sulfatase modifying selectively glycosaminoglycans and oligosaccharides: applications to synthesis and characterization of these compounds
A Perraut - 2011