Mesenchymal stem cell therapy for heart disease

M Gnecchi, E Cervio - Mesenchymal stem cell therapy, 2013 - Springer
Mesenchymal stem cells (MSC) are adult stem cells with capacity for self-renewal and multi-
lineage differentiation. Initially described in bone marrow, MSC are also present in other …

Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

[HTML][HTML] Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Mesenchymal stem cells in cardiology

IA White, C Sanina, W Balkan, JM Hare - Mesenchymal Stem Cells …, 2016 - Springer
Cardiovascular disease (CVD) accounts for more deaths globally than any other single
disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) …

Mesenchymal stem cells for cardiovascular regeneration

D Kuraitis, M Ruel, EJ Suuronen - Cardiovascular drugs and therapy, 2011 - Springer
Despite recent studies suggesting that the heart has instrinsic mechanisms of self-
regeneration following myocardial infarction, it cannot regenerate itself to an optimal level …

Mesenchymal stem cells and cardiac repair

C Nesselmann, N Ma, K Bieback… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• MSC isolation, characterization and standardization‐Isolation from different
sources‐Isolation under different culture conditions‐Characterization of MSCs …

Mesenchymal stem cell insights: prospects in cardiovascular therapy

SH Chou, SZ Lin, WW Kuo, P Pai, JY Lin… - Cell …, 2014 - journals.sagepub.com
Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …

Mesenchymal stem cells: future source for reparative medicine

R Bhatia, JM Hare - Congestive Heart Failure, 2005 - Wiley Online Library
Current treatments for ischemic cardiomyopathy are aimed toward minimizing the
deleterious consequences of damaged myocardium. The possibility of treating heart failure …

Mesenchymal stem cell therapy for treatment of cardiovascular disease: helping people sooner or later

P Trivedi, N Tray, T Nguyen, N Nigam… - Stem cells and …, 2010 - liebertpub.com
Despite advances in clinical management, cardiovascular disease remains the leading
cause of death in America. While cardiomyocytes retain limited plasticity following …