In this study, a pharmacokinetic-pharmacodynamic (PK-PD) target attainment analysis of
imipenem (IPM) in patients with impaired renal function was conducted. IPM (500mg) was …

Objective To determine the percentage of patients given standard doses of piperacillin/
tazobactam or meropenem by continuous infusion who achieved the target pharmacokinetic …

Introduction To enhance the probability of pharmacodynamic target attainment, piperacillin–
tazobactam can be administered as either a continuous or extended-infusion dosage …

(1) Objective: To describe the usefulness of a real-time therapeutic drug monitoring (TDM)-
based strategy for optimizing pharmacokinetic/pharmacodynamic (PK/PD) target attainment …

Objectives Infections with extended-spectrum-β-lactamase-producing organisms are an
increasing public health concern. We reviewed the use of an outpatient parenteral antibiotic …

Abstract Background Carbapenem-resistant Enterobacterales and multidrug resistant
Pseudomonas aeruginosa are global antimicrobial resistance threats. Cefepime …

The optimal regimens of piperacillin/sulbactam (PIS 2: 1), piperacillin/tazobactam (PTZ 8: 1),
and cefoperazone/sulbactam (CSL 2: 1) are not well defined in patients based on renal …

This was a prospective study to determine if pharmacokinetic/pharmacodynamic (PK/PD)-
based antibiotic dosing software aids in achieving concentration targets in critically ill …

We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39
bloodstream infections due to extended-spectrum-β-lactamase-producing Escherichia coli …

Purpose To evaluate target attainment of empirically dosed continuous infusion piperacillin/
tazobactam (TZP) and meropenem (MER) in critically ill patients. Patients and methods …