Ultrasensitive UPLC–MS/MS method for analysis of etheno-DNA adducts in human white blood cells
H Li, S Cui, S Wang, X Jiang, S Zhang… - Free Radical …, 2015 - Taylor & Francis
Etheno-DNA adducts are generated by interaction of cellular DNA with exogenous
environmental carcinogens and end products of lipid peroxidation. It has been determined …
environmental carcinogens and end products of lipid peroxidation. It has been determined …
Ultrasensitive UPLC-MS-MS method for the quantitation of etheno-DNA adducts in human urine
S Cui, H Li, S Wang, X Jiang, S Zhang… - International Journal of …, 2014 - mdpi.com
Etheno-DNA adducts are generated from the metabolism of exogenous carcinogens and
endogenous lipid peroxidation. We and others have previously reported that 1, N 6 …
endogenous lipid peroxidation. We and others have previously reported that 1, N 6 …
Effect of gender and cigarette smoking on urinary excretion of etheno DNA adducts in humans measured by isotope dilution gas chromatography/mass spectrometry
HJC Chen, CF Kao - Toxicology letters, 2007 - Elsevier
Endogenous formation of the promutagenic DNA adducts 1, N6-ethenoadenine (ɛAde) and
3, N4-ethenocytosine (ɛCyt) has been considered as biomarkers originated from lipid …
3, N4-ethenocytosine (ɛCyt) has been considered as biomarkers originated from lipid …
Simultaneous quantification of three lipid peroxidation-derived etheno adducts in human DNA by stable isotope dilution nanoflow liquid chromatography nanospray …
HJC Chen, GJ Lin, WP Lin - Analytical Chemistry, 2010 - ACS Publications
Etheno DNA adducts are promutagenic DNA lesions derived from exogenous industrial
chemicals, as well as endogenous sources including lipid peroxidation. Furthermore, levels …
chemicals, as well as endogenous sources including lipid peroxidation. Furthermore, levels …
Quantifying Etheno–DNA Adducts in Human Tissues, White Blood Cells, and Urine by Ultrasensitive 32P-Postlabeling and Immunohistochemistry
J Nair, UJ Nair, X Sun, Y Wang, K Arab… - … In Situ, Ex Vivo, and In …, 2011 - Springer
Exocyclic etheno–DNA adducts are formed by the reaction of lipid peroxidation products,
such as 4-hydroxy-2-nonenal (HNE) with DNA bases to yield 1, N 6-etheno-2 …
such as 4-hydroxy-2-nonenal (HNE) with DNA bases to yield 1, N 6-etheno-2 …
New ultrasensitive 32P-postlabelling method for the analysis of 3,N4-etheno-2′-deoxycytidine in human urine
X Sun, A Karlsson, H Bartsch, J Nair - Biomarkers, 2006 - Taylor & Francis
Etheno–DNA adducts are generated from exogenous carcinogens such as vinyl chloride
and urethane and also from endogenous lipid peroxidation products such as trans-4 …
and urethane and also from endogenous lipid peroxidation products such as trans-4 …
Quantification of Urinary Excretion of 1,N6-Ethenoadenine, a Potential Biomarker of Lipid Peroxidation, in Humans by Stable Isotope Dilution Liquid Chromatography …
HJC Chen, CM Chang - Chemical research in toxicology, 2004 - ACS Publications
Etheno DNA adducts are promutagenic DNA lesions derived from exogenous as well as
endogenous sources. The levels of etheno adducts in tissue DNA are elevated in cancer …
endogenous sources. The levels of etheno adducts in tissue DNA are elevated in cancer …
Effect of Cigarette Smoking on Urinary 3,N4-Ethenocytosine Levels Measured by Gas Chromatography/Mass Spectrometry
HJC Chen, CL Hong, CF Wu, WL Chiu - Toxicological Sciences, 2003 - academic.oup.com
Etheno DNA adducts are DNA damages derived from exogenous carcinogens as well as
endogenous lipid peroxidation and oxidative stress. Elevated levels of etheno DNA adducts …
endogenous lipid peroxidation and oxidative stress. Elevated levels of etheno DNA adducts …
Oxidative and alkylating damage in DNA
GR Martinez, APM Loureiro, SA Marques… - … Research/Reviews in …, 2003 - Elsevier
Modification of cellular DNA upon exposure to reactive oxygen and nitrogen species is the
likely initial event involved in the induction of the mutagenic and lethal effects of various …
likely initial event involved in the induction of the mutagenic and lethal effects of various …
Quantification of urinary etheno-DNA adducts by column-switching LC/APCI-MS/MS
PR Hillestrøm, A Weimann, HE Poulsen - … of the American Society for Mass …, 2006 - Springer
Lipid peroxidation induced etheno-DNA adducts are promutagenic and have been
suggested to play a causal role in the development of human cancers. Therefore, human …
suggested to play a causal role in the development of human cancers. Therefore, human …
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