The genetics of idiopathic clubfoot

F Dietz - Clinical Orthopaedics and Related Research (1976 …, 2002 - journals.lww.com
Idiopathic clubfoot is an uncommon congenital deformity that clusters in families but does
not fit typical Mendelian inheritance patterns. Studies done on twins, different incidences in …

Studies of TBX4 and chromosome 17q23.1q23.2: An uncommon cause of nonsyndromic clubfoot

W Lu, CA Bacino, BS Richards… - American Journal of …, 2012 - Wiley Online Library
Clubfoot is a common birth defect characterized by inward posturing and rigid downward
displacement of one or both feet. The etiology of syndromic forms of clubfoot is varied and …

Mid‐trimester ultrasound diagnosis of isolated talipes equinovarus: accuracy and outcome for infants

N Woodrow, T Iran, M Umstad… - Australian and New …, 1998 - Wiley Online Library
Seventeen fetuses were diagnosed with isolated congenital talipes equinovarus (CTEV) on
mid‐trimester ultrasound at the Royal Women's Hospital, Melbourne, between January …

[HTML][HTML] Functional Assessment of Clubfoot Associated HOXA9, TPM1, and TPM2 Variants Suggests a Potential Gene Regulation Mechanism

KS Weymouth, SH Blanton, T Powell, CV Patel… - … and Related Research®, 2016 - Springer
Background Isolated nonsyndromic clubfoot is a common birth defect affecting 135,000
newborns worldwide each year. Although treatment has improved, substantial long-term …

[HTML][HTML] Assessing public awareness of clubfoot and knowledge about the importance of early childhood treatment: a cross-sectional survey

A Alsiddiky, S Alrwibaah, A Alqahtani, A Alnujidi… - BMC pediatrics, 2019 - Springer
Background Clubfoot is a treatable abnormality that can be managed with early intervention.
However, there is a lack of public knowledge regarding clubfoot, which can delay treatment …

Congenital talipes equinovarus (clubfoot): a disorder of the foot but not the hand

Z Miedzybrodzka - Journal of anatomy, 2003 - Wiley Online Library
Idiopathic (non‐syndromic) congenital talipes equinovarus, or clubfoot, is a poorly
understood but common developmental disorder of the lower limb, which affects at least 2 …

Radiography and sonography of clubfoot: A comparative study

SK Bhargava, A Tandon, M Prakash, SS Arora… - Indian Journal of …, 2012 - Springer
Background: Congenital talipes equinovarus is a common foot deformity afflicting children
with reported incidence varying from 0.9/1000 to 7/1000 in various populations. The success …

The genetics of isolated and syndromic clubfoot

B Sadler, CA Gurnett… - Journal of children's …, 2019 - journals.sagepub.com
Purpose Congenital clubfoot is a serious birth defect that affects nearly 0.1% of all births.
Though there is strong evidence for a genetic basis of isolated clubfoot, aside from a handful …

Growth disturbance of the distal tibia in patients with idiopathic clubfeet: ankle valgus and anteflexion of the distal tibia

RD Burghardt, LP Tettenborn… - Journal of Pediatric …, 2016 - journals.lww.com
Background: The aim of this study was to evaluate the incidence of deformities of the distal
tibia in patients with idiopathic clubfeet who had undergone surgical intervention with a …

The Ponseti method decreased the surgical incidence in children with congenital clubfoot: a population-based, 8 birth-year cohort study

CH Chang, SM Wang, KN Kuo - JBJS, 2019 - journals.lww.com
Background: With the introduction of the Ponseti method for congenital clubfoot, the relapse
rate and the surgical rate have been remarkably reduced. However, data from population …