Visceral adipose tissue attacks beyond the liver: esophagogastric junction as a new target

H Tilg, AR Moschen - Gastroenterology, 2010 - gastrojournal.org
Given the worldwide increase in rates of obesity, the patient population with obesity-related
disorders has risen dramatically. Obesity predisposes individuals to a greater risk of …

Circulating levels of inflammatory and metabolic biomarkers and risk of esophageal adenocarcinoma and Barrett esophagus: systematic review and meta-analysis

SH Xie, S Rabbani, E Ness-Jensen… - … , Biomarkers & Prevention, 2020 - AACR
Associations between circulating levels of obesity-related biomarkers and risk of
esophageal adenocarcinoma and Barrett esophagus have been reported, but the results are …

Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation

OO Ogunwobi, ILP Beales - Molecular and cellular endocrinology, 2008 - Elsevier
Obesity increases the risk of developing several cancers including oesophageal
adenocarcinoma (OAC). Obesity is characterised by hyperleptinaemia and …

Obesity, metabolic syndrome and esophageal adenocarcinoma: epidemiology, etiology and new targets

AM Ryan, M Duong, L Healy, SA Ryan, N Parekh… - Cancer …, 2011 - Elsevier
Background: Rates of distal and junctional adenocarcinomas are increasing in Western
countries. Methods: Systematic review of epidemiological evidence linking obesity to …

Plasma leptin is independently associated with the intima-media thickness of the common carotid artery

M Ciccone, R Vettor, N Pannacciulli… - International journal of …, 2001 - nature.com
OBJECTIVE: To investigate whether intima-media thickness (IMT) of the common carotid
artery (CCA), an early marker of asymptomatic atherosclerosis, is significantly and …

Leptin and gastro‐intestinal malignancies

JM Howard, GP Pidgeon, JV Reynolds - Obesity Reviews, 2010 - Wiley Online Library
Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …

Is obesity associated with Barrett's esophagus and esophageal adenocarcinoma

KL Lynch - Gastroenterol Clin North Am, 2016 - books.google.com
The incidence of Barrett's esophagus and esophageal adenocarcinoma (EAC) has
increased over the past several decades in the Western world. The rise in obesity paralleled …

Abdominal obesity and body mass index as risk factors for Barrett's esophagus

DA Corley, A Kubo, TR Levin, G Block, L Habel… - Gastroenterology, 2007 - Elsevier
Background: Barrett's esophagus is a strong risk factor for esophageal adenocarcinoma, but
little is known about its associations with body mass index (BMI) or abdominal obesity …

Interaction between adiponectin and leptin influences the risk of colorectal adenoma

T Yamaji, M Iwasaki, S Sasazuki, S Tsugane - Cancer research, 2010 - AACR
Obesity has been associated with an increased risk of colorectal neoplasia, but the
mechanisms of this potential association have not been elucidated. We hypothesized that …

Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma

JM Howard, P Beddy, D Ennis, M Keogan… - Journal of British …, 2010 - academic.oup.com
Background Obesity is associated with oesophageal adenocarcinoma, but mechanisms
linking fat and carcinogenesis remain poorly understood. Altered circulating adipocytokines …