Rates of adenocarcinoma of the esophagus (EAC) and esophagogastric junction (EGJAC)
have been rising rapidly in recent decades, in contrast to the declining rates of esophageal …

Background High levels of serum leptin and low levels of serum adiponectin are strongly
correlated with obesity, a well-established risk factor for colorectal cancer (CRC). Growing …

PURPOSE: Associations of adiponectin and leptin and their ratio with body mass index
(BMI) and homeostasis model assessment of insulin resistance (HOMA-IR) have been …

Adipokines contribute to the inflammatory process which can lead to obesity-associated
cardiometabolic complications. Metabolically healthy obese individuals seem to be …

Obesity has been shown to be associated with an increased risk of both colorectal cancer
and adenomatous polyps. One mechanism underlying this relationship may involve the …

Adipokines are adipocyte-secreted hormones that may mediate the etiologic link between
obesity and colorectal cancer; however, the evidence from large prospective studies is …

The prevalence of obesity in the Japanese population has been increasing dramatically in
step with the Westernization of lifestyles and food ways. Our study demonstrated significant …

Regulation of adipokines in lean adults without metabolic disease and without eating
disorders has not been comprehensively elucidated. We hypothesized that some of the …

Background: We investigated the association between long-segment Barrett's esophagus
and obesity in the Japanese population in a multicenter case-control trial. Methods: One …

The aim of this prospective study was to evaluate the impact of obesity, determined by
different anthropometric measures, on clinical and endoscopic severity of GERD and the …