[HTML][HTML] Metabolomic patterns in adolescents with mild to moderate CKD
ER Brooks, DC Lin, CB Langman… - Kidney International …, 2019 - kireports.org
Metabolomic Patterns in Adolescents With Mild to Moderate CKD - Kidney International Reports
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Longitudinal plasma metabolome patterns and relation to kidney function and proteinuria in pediatric chronic kidney disease
Methods The Chronic Kidney Disease in Children (CKiD) study is a multi-institutional,
prospective cohort that enrolled children aged six-months to 16-years with estimated …
prospective cohort that enrolled children aged six-months to 16-years with estimated …
The Promise and Challenges of Metabolomic Studies in Pediatric CKD
S Kalim, WE Smoyer - Clinical Journal of the American Society of …, 2024 - journals.lww.com
Metabolomic studies, employing sophisticated analytical chemistry and statistical methods to
systematically study the collection of small molecules (typically, 1500 Daltons; eg., sugars …
systematically study the collection of small molecules (typically, 1500 Daltons; eg., sugars …
The promise of metabolomics in decelerating CKD progression in children
UT Schultheiss, P Sekula - … Journal of the American Society of …, 2021 - journals.lww.com
Metabolomics is defined as the quantification of small molecules (usually, 1500 Daltons)
within a biologic specimen (eg, plasma)(1). Detectable metabolites belong to various …
within a biologic specimen (eg, plasma)(1). Detectable metabolites belong to various …
Plasma Metabolome Differences Across Time in Pediatric CKD: FR-PO408
Background: Studies of longitudinal metabolomics in CKD are lacking. Baseline metabolite
levels have been associated with risk of future CKD progression (PMC8455058). The …
levels have been associated with risk of future CKD progression (PMC8455058). The …
Using machine learning to identify metabolomic signatures of pediatric chronic kidney disease etiology
Background Untargeted plasma metabolomic profiling combined with machine learning
(ML) may lead to discovery of metabolic profiles that inform our understanding of pediatric …
(ML) may lead to discovery of metabolic profiles that inform our understanding of pediatric …
A systematic review of metabolomic findings in adult and pediatric renal disease
L Moritz, A Schumann, M Pohl, A Köttgen… - Clinical …, 2023 - Elsevier
Chronic kidney disease (CKD) affects over 0.5 billion people worldwide across their
lifetimes. Despite a growingly ageing world population, an increase in all-age prevalence of …
lifetimes. Despite a growingly ageing world population, an increase in all-age prevalence of …
Metabolite biomarkers of CKD progression in children
MR Denburg, Y Xu, AG Abraham… - Clinical Journal of the …, 2021 - journals.lww.com
Results Baseline characteristics were 391 (61%) male; median age 12 years; median eGFR
54 ml/min per 1.73 m 2; 448 (69%) nonglomerular diagnosis. Over a median follow-up of 4.8 …
54 ml/min per 1.73 m 2; 448 (69%) nonglomerular diagnosis. Over a median follow-up of 4.8 …
Consistency of metabolite associations with measured glomerular filtration rate in children and adults
Background There is interest in identifying novel filtration markers that lead to more accurate
GFR estimates than current markers (creatinine and cystatin C) and are more consistent …
GFR estimates than current markers (creatinine and cystatin C) and are more consistent …
Circulating Metabolomic Associations with Neurocognitive Outcomes in Pediatric CKD
Background: Children with chronic kidney disease (CKD) are at risk for impaired
neurocognitive functioning. We investigated metabolomic associations with neurocognition …
neurocognitive functioning. We investigated metabolomic associations with neurocognition …