[HTML][HTML] Monitoring type 2 diabetes from volatile faecal metabolome in Cushing's syndrome and single Afmid mouse models via a longitudinal study

C Lourenço, D Kelly, J Cantillon, M Cauchi, MA Yon… - Scientific reports, 2019 - nature.com
The analysis of volatile organic compounds (VOCs) as a non-invasive method for disease
monitoring, such as type 2 diabetes (T2D) has shown potential over the years although not …

[HTML][HTML] Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes

FM Calabrese, VA Genchi, N Serale, G Celano… - Journal of …, 2024 - Springer
Background People with metabolically healthy (MHO) and metabolically unhealthy obesity
(MUO) differ for the presence or absence of cardio-metabolic complications, respectively …

[HTML][HTML] Elevated levels of proinflammatory volatile metabolites in feces of high fat diet fed KK-Ay mice

M Uchikawa, M Kato, A Nagata, S Sanada… - Scientific Reports, 2020 - nature.com
When the microfloral composition deteriorates, it triggers low-level chronic inflammation
associated with several lifestyle-related diseases including obesity and diabetic mellitus …

[HTML][HTML] Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition

I Zarei, VM Koistinen, M Kokla, A Klåvus, AF Babu… - Scientific Reports, 2022 - nature.com
The essential role of gut microbiota in health and disease is well recognized, but the
biochemical details that underlie the beneficial impact remain largely undefined. To maintain …

[HTML][HTML] Sex-dependent effects on the gut microbiota and host metabolome in type 1 diabetic mice

X Zhang, D Wang, Y Zheng, Y Tu, Q Xu, H Jiang… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Sexual dimorphism exists in the onset and development of type 1 diabetes (T1D), but its
potential pathological mechanism is poorly understood. In the present study, we examined …

Integrative Analysis of the Gut Microbiota and Metabolome in Obese Mice with Electroacupuncture by 16S rRNA Gene Sequencing and HPLC–MS-based Metabolic …

YC Si, CC Ren, EW Zhang, ZX Kang… - The American Journal …, 2022 - World Scientific
Acupuncture has been used to treat numerous diseases such as obesity in China for
thousands of years. Several mechanisms of acupuncture on obesity have been surveyed …

[HTML][HTML] Metabolomic signatures for liver tissue and cecum contents in high-fat diet-induced obese mice based on UHPLC-Q-TOF/MS

H Cai, Z Wen, K Meng, P Yang - Nutrition & Metabolism, 2021 - Springer
Background The incidence of obesity is increasing worldwide, and it is a risk factor for
diabetes, dyslipidemia, and nonalcoholic fatty liver disease. Our previous study had …

Importance of sulfur-containing metabolites in discriminating fecal extracts between normal and type-2 diabetic mice

A Walker, M Lucio, B Pfitzner… - Journal of proteome …, 2014 - ACS Publications
A metabolic disorder such as Type-2 Diabetes mellitus (T2DM) is a complex disease
induced by genetic, environmental, and nutritional factors. The db/db mouse model, bearing …

[HTML][HTML] Multi-omics characterization of type 2 diabetes mellitus-induced gastroenteropathy in the db/db mouse model

Y Zhang, Y Zhang, R Yin, X Fang, R Miao… - Frontiers in Cell and …, 2024 - frontiersin.org
Objective Gastrointestinal dysfunction are often associated with type 2 diabetes mellitus
(T2DM), a complicated metabolic illness. Contributing factors have been proposed …

[PDF][PDF] Optimisation of sample preparation for direct SPME-GC-MS analysis of murine and human faecal volatile organic compounds for metabolomic studies

S Reade, A Mayor, R Aggio, T Khalid… - J Anal Bioanal …, 2014 - researchgate.net
The analysis of volatile organic compounds (VOCs) emitted from biological fluids such as
blood, urine, breath and faeces, has been receiving more attention from researchers and …