Of the thousands of proven carcinogens and toxic agents contained within a cigarette,
nicotine, while being the addictive agent, is often viewed as the least harmful of these …

Nicotinic acetylcholine receptors are not only expressed by the nervous system and at the
neuro-muscular junction but also by mononuclear phagocytes, which belong to the innate …

Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Nicotinic acetylcholine receptors (nAChR) are diverse members of the ligand-gated ion
channel superfamily of neurotransmitter receptors and principal biological targets of nicotine …

The expression of nicotinic acetylcholine receptors by neurons, microglia, and astrocytes
suggests possibly diverse mechanisms by which natural nicotinic cholinergic signaling and …

Nicotine addiction and other forms of drug addiction continue to be significant public health
problems in the United States and the rest of the world. Accumulated evidence indicates that …

Nicotinic acetylcholine receptors (nAChRs) exist as a diverse family of physiologically
important ligand-gated ion channels active in classic, excitatory neurotransmission and …

In the 25 years since the observation that chronic exposure to nicotine could regulate the
number and function of high affinity nicotine binding sites in the brain there has been a …

Nicotine achieves its psychopharmacological effects by interacting with nicotinic
acetylcholine receptors (nAChRs) in the brain. There are numerous subtypes of nAChR that …

Recent advances concerning effects of chronic nicotine exposure on nicotinic acetylcholine
receptor (nAChR) expression are reviewed. Implications are assessed of these findings for …