THU023 Sparse Granulation In Growth Hormone Secreting Adenomas: Clinical Implications Of A Rare Histological Finding

A Merrill, R Varughese, G Campbell… - Journal of the …, 2023 - academic.oup.com
Abstract Disclosure: A. Merrill: None. R. Varughese: None. G. Campbell: None. L.
Belalcazar: None. Introduction: Acromegaly is an uncommon disease. Endocrinologists may …

Pasireotide: successful treatment of a sparsely granulated tumour in a resistant case of acromegaly

W Amarawardena, KD Liyanarachchi… - … & Metabolism Case …, 2017 - edm.bioscientifica.com
The granulation pattern of somatotroph adenomas is well known to be associated with
differing clinical and biochemical characteristics, and it has been shown that sparsely …

Adenoma granulation pattern correlates with clinical variables and effect of somatostatin analogue treatment in a large series of patients with acromegaly

SL Fougner, O Casar‐Borota, A Heck… - Clinical …, 2012 - Wiley Online Library
Context Somatotroph adenomas have been classified into densely granulated (DG) and
sparsely granulated (SG) tumours with a transitional, intermediate group. Gsp oncogenes …

Granulation pattern, but not GSP or GHR mutation, is associated with clinical characteristics in somatostatin-naïve patients with somatotroph adenomas

S Larkin, R Reddy, N Karavitaki, S Cudlip… - European journal of …, 2013 - academic.oup.com
Objective Somatotroph adenomas causing acromegaly are histologically classified into
densely granulated (DG) and sparsely granulated (SG) subtypes with different morphology …

Abstract# 1398813: A Rare Case of Acromegaly with Negative Immunohistochemical Staining for Growth Hormone

J Rosenwasser, M Candelario-Cosme… - Endocrine …, 2023 - endocrinepractice.org
Discussion Clinical suspicion for acromegaly is confirmed by elevated IGF-1 and GH levels.
When a GH-secreting pituitary adenoma is resected, immunocytochemistry with GH staining …

# 1704665 A Giant Tumor Unveiled: A Case Report of A Massive Pituitary Adenoma Inducing Early-onset Acromegaly

CA Balasubramaniapandia… - Endocrine Practice, 2024 - Elsevier
Discussion The young age at presentation makes this case atypical for acromegaly. He had
classic symptoms of acromegaly and found to have markedly elevated IGF-1 levels. The …

FRI292 Asymptomatic TSH Secreting Pituitary Macroadenoma

B Gautam, MS Hossain, H Liao… - Journal of the …, 2023 - academic.oup.com
Abstract Disclosure: B. Gautam: None. MS Hossain: None. H. liao: None. K. Mandal: None.
DS Rosenthal: None. SC Kumar: None. Introduction: TSH-producing adenoma is a rare …

Clinical, biological, radiological, and pathological comparison of sparsely and densely granulated somatotroph adenomas: a single center experience from a cohort of …

AA Swanson, D Erickson, DM Donegan, SM Jenkins… - Pituitary, 2021 - Springer
Purpose Growth hormone-producing pituitary adenomas are divided into two clinically
relevant histologic subtypes, densely (DG-A) and sparsely (SG-A) granulated. Histologic …

Non-functioning granulomatous pituitary adenoma: Common pathology in an unlikely site

LJ ZM, T Purewal, K Grounds… - Endocrine …, 2022 - endocrine-abstracts.org
Background: Tuberculosis (TB) is an important cause of mortality and morbidity globally.
Only a small proportion cases of systemic TB present with lesions spreading to meninges …

Caracterización de tumores secretores de hormona de crecimiento de acuerdo al patrón granular y su rol en el pronóstico

F Valenzuela, P Villanueva, D Rojas… - Revista médica de …, 2019 - SciELO Chile
VALENZUELA, Felipe et al. Caracterización de tumores secretores de hormona de
crecimiento de acuerdo al patrón granular y su rol en el pronóstico. Rev. méd. Chile [online] …