The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Nanoparticles, lung injury, and the role of oxidant stress

AK Madl, LE Plummer, C Carosino… - Annual review of …, 2014 - annualreviews.org
The emergence of engineered nanoscale materials has provided significant advancements
in electronic, biomedical, and material science applications. Both engineered nanoparticles …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

[PDF][PDF] The role of reactive oxygen species and oxidative stress in mediating particulate matter injury

T Xia, M Kovochich, A Nel - Clin Occup Environ Med, 2006 - academia.edu
Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
We review the literature indicating that the adverse health effects of ambient particulate
matter involve the generation of oxidative stress and inflammation, as well as …

Particulate matter induces tissue oxinflammation: from mechanism to damage

G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Oxidative stress and oxidative damage are central hypothetical mechanisms
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …

Nanoparticle-induced pulmonary toxicity

JJ Li, S Muralikrishnan, CT Ng… - Experimental biology …, 2010 - journals.sagepub.com
In recent decades, advances in nanotechnology engineering have given rise to the rapid
development of many novel applications in the biomedical field. However, studies into the …

Particulate matter air pollution and respiratory impact on humans and animals

C Losacco, A Perillo - Environmental Science and Pollution Research, 2018 - Springer
Air pollution is now fully acknowledged to be a public health problem and a social issue.
Particulate matter (PM) concentration has been linked with several clinical manifestations of …

Air pollution causing oxidative stress

Z Leni, L Künzi, M Geiser - Current opinion in toxicology, 2020 - Elsevier
Air pollution remains a major factor for adverse health effects and premature death
worldwide. Particulate matter with aerodynamic diameter≤ 2.5 μm (PM 2.5), mainly …