Background Masticatory muscle pain may occur following immediate occlusal alteration by
dental treatment. The underlying mechanisms are poorly understood. Transient receptor …

This study aimed to explore the role of acid-sensing ion channel 3 (ASIC3) in the modulation
of tooth mechanical hyperalgesia induced by orthodontic tooth movement. In male Sprague …

Pain in masticatory muscles is among the most prominent symptoms of temperomandibular
disorders (TMDs) that have diverse and complex etiology. A common complaint of TMD is …

Acute occlusal interference following improper occlusal alteration in dental practice can
induce chronic masticatory muscle pain. The underlying mechanism has not been clarified …

Temporomandibular joint or related masticatory muscle pain represents the most common
chronic orofacial pain condition. Patients frequently report this kind of pain after dental …

We previously showed that magnesium sulfate (MS) has systemic antinociceptive and local
peripheral pronociceptive effects. The role of transient receptor potential (TRP) channels …

The exact mechanism of the masseter muscle pain recognized as a prominent symptom in
temporomandibular disorders remains unclear, although it is clinically known that excessive …

Musculoskeletal pain conditions, particularly those associated with temporomandibular
disorders (TMD) affect a large percentage of the population. Identifying mechanisms …

The roles of ion channels in sensory neurons were examined in experimental models of
muscle pain in the rat. Rats were injected with 50μl of 4% carrageenan or subjected to an …

The exact mechanism underlying chronic masseter muscle pain, a conspicuous symptom in
temporomandibular disorder, remains unclear. We investigated whether expression of P2X3 …