Several highly pathogenic mammarenaviruses cause severe hemorrhagic and neurologic
disease in humans, for which vaccines and antivirals are limited or unavailable. New World …

Marburg virus (MARV) is a virus of high human consequence with a case fatality rate of 24–
88%. The global health and national security risks posed by Marburg virus disease (MVD) …

Marburg virus (MARV) is the causative agent of hemorrhagic fever outbreaks with high case
fatality rates. Closely related to Ebola virus, MARV is a filamentous virus with a negative …

Abstract The Angolan strain of Marburg virus (MARV/Ang) can cause lethal disease in
humans with a case fatality rate of up to 90%, but infection of immunocompetent rodents do …

Marburg virus (MARV) can cause lethal hemorrhagic fever in humans. Handling of MARV is
restricted to high-containment biosafety level 4 (BSL-4) facilities, which greatly impedes …

Until recently, immune responses in filovirus survivors remained poorly understood. Early
studies revealed IgM and IgG responses to infection with various filoviruses, but recent …

Filoviruses are causative agents of hemorrhagic fever, and to date no effective vaccine or
therapeutic has been approved to combat infection. Filovirus glycoprotein (GP) is the critical …

Transmission of hemorrhagic fever New World arenaviruses from their rodent reservoirs to
human populations poses substantial public health and economic dangers. These zoonotic …

Filoviruses (family Filoviridae) include five ebolaviruses and Marburg virus. These
pathogens cause a rapidly progressing and severe viral disease with high mortality rates …

Mucosal-associated invariant T cells are a unique population of T cells that express a semi-
invariant αβ TCR and are restricted by the MHC class I-related molecule MR1. MAIT cells …