Cellular uptake of nanoparticles versus small molecules: a matter of size

J Mosquera, I García… - Accounts of chemical …, 2018 - ACS Publications
Conspectus The primary function of the cell membrane is to protect cells from their
surroundings. This entails a strict regulation on controlling the exchange of matter between …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Cellular uptake of nanoparticles: journey inside the cell

S Behzadi, V Serpooshan, W Tao, MA Hamaly… - Chemical society …, 2017 - pubs.rsc.org
Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

Nanoparticles: Taking a unique position in medicine

TM Joseph, D Kar Mahapatra, A Esmaeili, Ł Piszczyk… - Nanomaterials, 2023 - mdpi.com
The human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In
parallel with our history of civilization, interest in scientific approaches to unravel …

Insight into cellular uptake and intracellular trafficking of nanoparticles

P Foroozandeh, AA Aziz - Nanoscale research letters, 2018 - Springer
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

Unexpected size effect: the interplay between different‐sized nanoparticles in their cellular uptake

L Li, WS Xi, Q Su, Y Li, GH Yan, Y Liu, H Wang, A Cao - Small, 2019 - Wiley Online Library
The size effect on the cellular uptake of nanoparticles (NPs) has been extensively studied,
but it is still not well understood. Herein, a reductionist approach is used to minimize all …

[HTML][HTML] Nanoparticle interactions with live cells: quantitative fluorescence microscopy of nanoparticle size effects

L Shang, K Nienhaus, X Jiang, L Yang… - Beilstein journal of …, 2014 - beilstein-journals.org
Engineered nanomaterials are known to enter human cells, often via active endocytosis.
Mechanistic details of the interactions between nanoparticles (NPs) with cells are still not …

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

A review on nanotechnology: Properties, applications, and mechanistic insights of cellular uptake mechanisms

S Khan, S Mansoor, Z Rafi, B Kumari, A Shoaib… - Journal of Molecular …, 2022 - Elsevier
Nanotechnology is a relatively new field of science and technology that studies tiny objects
(0.1–100 nm). Due to various positive attributes displayed by the biogenic synthesis of …

Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects

S Barua, S Mitragotri - Nano today, 2014 - Elsevier
Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …