Insights into cellular uptake of nanoparticles
M Hasanzadeh Kafshgari, FJ Harding… - Current drug …, 2015 - ingentaconnect.com
Nanomaterials promise to improve disease diagnosis and treatment by enhancing the
delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In …
delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In …
Nanoparticle uptake: the phagocyte problem
HH Gustafson, D Holt-Casper, DW Grainger… - Nano today, 2015 - Elsevier
Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …
Nanoparticles: pharmacological and toxicological significance
C Medina, MJ Santos‐Martinez… - British journal of …, 2007 - Wiley Online Library
Nanoparticles are tiny materials (< 1000 nm in size) that have specific physicochemical
properties different to bulk materials of the same composition and such properties make …
properties different to bulk materials of the same composition and such properties make …
Influence of nanoparticle shape, size, and surface functionalization on cellular uptake
N Ma, C Ma, C Li, T Wang, Y Tang… - … of nanoscience and …, 2013 - ingentaconnect.com
With the rapid development of biotechnology and nanomedicine, extensive research has
focused on the investigations of delivering large-cargo molecules using nanoparticles …
focused on the investigations of delivering large-cargo molecules using nanoparticles …
Nanoparticles in modern medicine: state of the art and future challenges
SK Murthy - International journal of nanomedicine, 2007 - Taylor & Francis
Nanoparticles are materials with overall dimensions in the nanoscale, ie, under 100 nm. In
recent years, these materials have emerged as important players in modern medicine, with …
recent years, these materials have emerged as important players in modern medicine, with …
Identification of multiple cellular uptake pathways of polystyrene nanoparticles and factors affecting the uptake: Relevance for drug delivery systems
R Firdessa, TA Oelschlaeger, H Moll - European journal of cell biology, 2014 - Elsevier
Nanoparticles may address challenges by human diseases through improving diagnosis,
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …
Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution
MA Dobrovolskaia, P Aggarwal, JB Hall… - Molecular …, 2008 - ACS Publications
Nanoparticles have unique physicochemical properties which make them promising
platforms for drug delivery. However, immune cells in the bloodstream (such as monocytes …
platforms for drug delivery. However, immune cells in the bloodstream (such as monocytes …
The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
Multifunctional nanoparticles: recent progress in cancer therapeutics
Although much progress has been made in treating cancers, cancer death rates in and
around the United States are still high. Current treatments are either ineffective against some …
around the United States are still high. Current treatments are either ineffective against some …
Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population
Nanoparticles are considered a primary vehicle for targeted therapies because they can
pass biological barriers and enter and distribute within cells by energy-dependent …
pass biological barriers and enter and distribute within cells by energy-dependent …