Exploring pharmacological significance of chalcone scaffold: a review

NK Sahu, SS Balbhadra… - Current medicinal …, 2012 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …

[HTML][HTML] Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Trends in utilization of the pharmacological potential of chalcones

DI Batovska, IT Todorova - Current clinical pharmacology, 2010 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are open chain flavonoids that are widely
biosynthesized in plants. They are important for the pigmentation of flowers and, hence, act …

Recent developments in biological activities of chalcones: A mini review

P Singh, A Anand, V Kumar - European journal of medicinal chemistry, 2014 - Elsevier
Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …

[PDF][PDF] Chemical and structural properties of chalcones I

BE Aksöz, R Ertan - Fabad J Pharm Sci, 2011 - dergi.fabad.org.tr
Chalcones belong to the flavonoid family and display several pharmacological activities
which are very important. They can be used as an initial compound for synthesis of a lot of …

[HTML][HTML] Pharmacotherapeutics applications and chemistry of chalcone derivatives

JS Dhaliwal, S Moshawih, KW Goh, MJ Loy… - Molecules, 2022 - mdpi.com
Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …

Recent advances in therapeutic chalcones

L Ni, CQ Meng, JA Sikorski - Expert Opinion on Therapeutic Patents, 2004 - Taylor & Francis
Naturally-occurring and synthetic chalcone compounds have shown promising biological
activity and safety profiles and have the potential to be developed as, or more properly …

Chalcones: A review on synthesis and pharmacological activities

K Goyal, R Kaur, A Goyal, R Awasthi - Journal of Applied …, 2021 - japsonline.com
Chalcone is a privileged species with medicinal significance as it consists of reactive
ketoethylenic moiety–CO–CH= CH–belonging to flavonoids. The presence of a reactive α, β …

Synthesis, reactions and application of chalcones: A systematic review

MA Shalaby, SA Rizk, AM Fahim - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …

[HTML][HTML] Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

J Higgs, C Wasowski, A Marcos, M Jukič, CH Paván… - Heliyon, 2019 - cell.com
Anxiety disorders, depression and pain are highly prevalent pathologies. Their
pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to …