Mesenchymal stem cell-laden hydrogel microfibers for promoting nerve fiber regeneration in long-distance spinal cord transection injury

S Yao, F He, Z Cao, Z Sun, Y Chen… - ACS Biomaterials …, 2020 - ACS Publications
Mesenchymal stem cell (MSC)-based regenerative medicine is widely considered as a
promising approach for repairing tissue and re-establishing function in spinal cord injury …

Recellularized nerve allografts with differentiated mesenchymal stem cells promote peripheral nerve regeneration

Y Wang, Z Zhao, Z Ren, B Zhao, L Zhang, J Chen… - Neuroscience …, 2012 - Elsevier
Chemical-extracted acellular nerve allografting, containing the natural nerve structure and
elementary nerve extracellular matrix (ECM), has been used for peripheral nerve-defect …

The effect of Matrigel as scaffold material for neural stem cell transplantation for treating spinal cord injury

J Wang, R Chu, N Ni, G Nan - Scientific reports, 2020 - nature.com
Traumatic injury to the spinal cord causes permanent loss of function and major personal,
social, and economic problems. Cell-based delivery strategies is a promising approach for …

[HTML][HTML] Engraftment, neuroglial transdifferentiation and behavioral recovery after complete spinal cord transection in rats

L Sabino, CA Maria, L Luca, V Valerio… - Surgical Neurology …, 2018 - ncbi.nlm.nih.gov
Background: Proof of the efficacy and safety of a xenogeneic mesenchymal stem cell
(MSCs) transplant for spinal cord injury (SCI) may theoretically widen the spectrum of …

Promotion of survival and differentiation of neural stem cells with fibrin and growth factor cocktails after severe spinal cord injury

P Lu, L Graham, Y Wang, D Wu… - JoVE (Journal of Visualized …, 2014 - jove.com
Neural stem cells (NSCs) can self-renew and differentiate into neurons and glia.
Transplanted NSCs can replace lost neurons and glia after spinal cord injury (SCI), and can …

Reduction of cystic cavity, promotion of axonal regeneration and sparing, and functional recovery with transplanted bone marrow stromal cell–derived Schwann cells …

Y Someya, M Koda, M Dezawa, T Kadota… - … of Neurosurgery: Spine, 2008 - thejns.org
Object The authors previously reported that Schwann cells (SCs) could be derived from
bone marrow stromal cells (BMSCs) in vitro and that they promoted axonal regeneration of …

Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats

DP Ankeny, DM McTigue, LB Jakeman - Experimental neurology, 2004 - Elsevier
Contusive spinal cord injury (SCI) produces large fluid-, debris-and inflammatory cell-filled
cystic cavities that lack structure to support significant axonal regeneration. The recent …

Therapeutic effect of biomimetic scaffold loaded with human amniotic epithelial cell-derived neural-like cells for spinal cord injury

C Qiu, Y Sun, J Li, Y Xu, J Zhou, C Qiu, S Zhang, Y He… - Bioengineering, 2022 - mdpi.com
Spinal cord injury (SCI) results in devastating consequences for the motor and sensory
function of patients due to neuronal loss and disrupted neural circuits, confronting poor …

Long-term survival and outgrowth of mechanically engineered nervous tissue constructs implanted into spinal cord lesions

A Iwata, KD Browne, BJ Pfister, JA Gruner… - Tissue …, 2006 - liebertpub.com
While most approaches to repair spinal cord injury (SCI) rely on promoting axon outgrowth,
the extensive distance that axons would have to grow to bridge SCI lesions remains an …

Application of marrow mesenchymal stem cell‐derived extracellular matrix in peripheral nerve tissue engineering

Y Gu, Z Li, J Huang, H Wang, X Gu… - Journal of Tissue …, 2017 - Wiley Online Library
To advance molecular and cellular therapy into the clinic for peripheral nerve injury,
modification of neural scaffolds with the extracellular matrix (ECM) of peripheral nerves has …