The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …

Untargeted, global metabolite profiling (often described as metabonomics or metabolomics)
represents an expanding research topic and is, potentially, a major pillar for systems biology …

Metabolomics, the global study of small molecules in a particular system, has in the past few
years risen to become a primary-omics platform for the study of metabolic processes. With …

Metabolomics is a critical member in systems biology. Although great progress has been
achieved in metabolomics, there are still some problems in sample preparation, data …

Metabolomics has become an invaluable tool for both studying metabolism and biomarker
discovery. The great technical advances in analytical chemistry and bioinformatics have …

Quantitative metabolomics is under intense development, and no commonly accepted
standard analytical technique has emerged, yet. The employed analytical methods were …

Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …

Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical
strategies have brought about great progress in targeted metabolomics analysis. This …

In recent years, metabolomics has emerged as a pivotal approach for the holistic analysis of
metabolites in biological systems. The rapid progress in analytical equipment, coupled to the …

Because of great diversity of chemical and physical properties and wide ranges of
concentrations of different metabolites in metabolome samples, metabolome analysis is a …