Unraveling the intoxicating and therapeutic effects of cannabis ingredients on psychosis and cognition

M Colizzi, M Ruggeri, S Bhattacharyya - Frontiers in psychology, 2020 - frontiersin.org
Research evidence suggests a dose–response relationship for the association between
cannabis use and risk of psychosis. Such relationship seems to reflect an increased risk of …

Neurocognitive effects of cannabis: Lessons learned from human experimental studies

M Colizzi, S Bhattacharyya - Progress in brain research, 2018 - Elsevier
The following chapter offers an overview of results of experimental studies conducted
among healthy individuals examining the effects of acute administration of Δ9-THC and …

Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

A Englund, PD Morrison, J Nottage… - Journal of …, 2013 - journals.sagepub.com
Community-based studies suggest that cannabis products that are high in Δ9-
tetrahydrocannabinol (THC) but low in cannabidiol (CBD) are particularly hazardous for …

[HTML][HTML] Cannabis with high cannabidiol content is associated with fewer psychotic experiences

CD Schubart, IEC Sommer, WA van Gastel… - Schizophrenia …, 2011 - Elsevier
OBJECTIVE: Cannabis is associated with psychotic outcomes in numerous studies, an effect
that is commonly attributed to Δ 9-tetrahydrocannabinol (Δ 9-THC). An increasing number of …

Modulation of acute effects of delta-9-tetrahydrocannabinol on psychotomimetic effects, cognition and brain function by previous cannabis exposure

M Colizzi, P McGuire, V Giampietro, S Williams… - European …, 2018 - Elsevier
Cannabis use has been associated with psychosis and cognitive dysfunction. Some
evidence suggests that the acute behavioral and neurocognitive effects of the main active …

Does cannabis composition matter? Differential effects of delta-9-tetrahydrocannabinol and cannabidiol on human cognition

M Colizzi, S Bhattacharyya - Current Addiction Reports, 2017 - Springer
Abstract Purpose of Review The lack of clarity about the effect of cannabis use on cognition
may be attributable to the considerable heterogeneity among studies in terms of cannabis …

Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis

G Hindley, K Beck, F Borgan, CE Ginestet… - The Lancet …, 2020 - thelancet.com
Background Approximately 188 million people use cannabis yearly worldwide, and it has
recently been legalised in 11 US states, Canada, and Uruguay for recreational use. The …

The Yin and Yang of Cannabis: a systematic review of human neuroimaging evidence of the differential effects of Δ9-tetrahydrocannabinol and cannabidiol

B Gunasekera, C Davies, R Martin-Santos… - Biological Psychiatry …, 2021 - Elsevier
Abstract Cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC) have been the most
investigated cannabinoids at the human and preclinical levels, although the neurobiological …

The acute effects of synthetic intravenous Δ9-tetrahydrocannabinol on psychosis, mood and cognitive functioning

PD Morrison, V Zois, DA McKeown, TD Lee… - Psychological …, 2009 - cambridge.org
BackgroundRecent work suggests that heavy use of cannabis is associated with an
increased risk of schizophrenia-like psychosis. However, there is a dearth of experimental …

Opposite roles for cannabidiol and δ-9-tetrahydrocannabinol in psychotomimetic effects of cannabis extracts: a naturalistic controlled study

A Sainz-Cort, D Jimenez-Garrido… - Journal of Clinical …, 2021 - journals.lww.com
Background Although δ-9-tetrahydrocannabinol (THC), the main cannabinoid from the
cannabis plant, is responsible for the psychotomimetic effects of cannabis, cannabidiol …