A data-driven approach to preprocessing Illumina 450K methylation array data

R Pidsley, CC Y Wong, M Volta, K Lunnon, J Mill… - BMC genomics, 2013 - Springer
Background As the most stable and experimentally accessible epigenetic mark, DNA
methylation is of great interest to the research community. The landscape of DNA …

Complete Pipeline for Infinium® Human Methylation 450K BeadChip Data Processing Using Subset Quantile Normalization for Accurate DNA Methylation Estimation

N Touleimat, J Tost - Epigenomics, 2012 - Taylor & Francis
Background: Huge progress has been made in the development of array-or sequencing-
based technologies for DNA methylation analysis. The Illumina Infinium® Human …

missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform

B Phipson, J Maksimovic, A Oshlack - Bioinformatics, 2015 - academic.oup.com
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …

An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

F Marabita, M Almgren, ME Lindholm, S Ruhrmann… - Epigenetics, 2013 - Taylor & Francis
The proper identification of differentially methylated CpGs is central in most epigenetic
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …

Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi

JP Fortin, TJ Triche Jr, KD Hansen - Bioinformatics, 2017 - academic.oup.com
The minfi package is widely used for analyzing Illumina DNA methylation array data. Here
we describe modifications to the minfi package required to support the …

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins… - …, 2012 - academic.oup.com
The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density
microarray for quantifying the methylation level of over 450 000 CpG sites within human …

ChAMP: 450k chip analysis methylation pipeline

TJ Morris, LM Butcher, A Feber, AE Teschendorff… - …, 2014 - academic.oup.com
Abstract The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-
throughput DNA methylation analysis. Several methods for normalization and processing of …

Considerations for normalization of DNA methylation data by Illumina 450K BeadChip assay in population studies

P Yousefi, K Huen, RA Schall, A Decker… - Epigenetics, 2013 - Taylor & Francis
Analysis of epigenetic mechanisms, particularly DNA methylation, is of increasing interest for
epidemiologic studies examining disease etiology and impacts of environmental exposures …

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

EM Price, AM Cotton, LL Lam, P Farré, E Emberly… - Epigenetics & …, 2013 - Springer
Background Measurement of genome-wide DNA methylation (DNAm) has become an
important avenue for investigating potential physiologically-relevant epigenetic changes …

SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips

J Maksimovic, L Gordon, A Oshlack - Genome biology, 2012 - Springer
DNA methylation is the most widely studied epigenetic mark and is known to be essential to
normal development and frequently disrupted in disease. The Illumina …