[HTML][HTML] Extracellular vesicles as biomarkers and therapeutic tools: from pre-clinical to clinical applications

MC Ciferri, R Quarto, R Tasso - Biology, 2021 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are membrane-bound vesicles released by all
cell types, differing in biogenesis, physical characteristics, and contents. Due to their central …

Therapeutic and diagnostic applications of extracellular vesicles

S Stremersch, SC De Smedt, K Raemdonck - Journal of Controlled Release, 2016 - Elsevier
During the past two decades, extracellular vesicles (EVs) have been identified as important
mediators of intercellular communication, enabling the functional transfer of bioactive …

Subpopulations of extracellular vesicles and their therapeutic potential

C Lässer, SC Jang, J Lötvall - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …

Biomedical application of small extracellular vesicles in cancer treatment

S Araujo-Abad, M Saceda… - Advanced drug delivery …, 2022 - Elsevier
Extracellular vesicles (EVs) are produced by almost all cell types in vivo or in vitro. Among
them, exosomes are small nanovesicles with a lipid bilayer, proteins and RNAs actively …

Extracellular vesicles: intelligent delivery strategies for therapeutic applications

A Pinheiro, AM Silva, JH Teixeira… - Journal of controlled …, 2018 - Elsevier
Extracellular vesicles (EV), in particular exosomes, have been the object of intense
research, due to their potential to mediate intercellular communication, modulating the …

[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Progress in extracellular vesicle biology and their application in cancer medicine

A Srivastava, N Amreddy, V Pareek… - Wiley …, 2020 - Wiley Online Library
Under the broader category of extracellular vesicles (EVs), exosomes are now well
recognized for their contribution and potential for biomedical research. During the last ten …

[HTML][HTML] Extracellular vesicles in blood: sources, effects, and applications

A Alberro, L Iparraguirre, A Fernandes… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are important players for intercellular communication. EVs are
secreted by almost all cell types; they can transfer information between nearby or distant …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

[HTML][HTML] Extracellular vesicles as potential biomarkers and therapeutic approaches in autoimmune diseases

K Xu, Q Liu, K Wu, L Liu, M Zhao, H Yang… - Journal of Translational …, 2020 - Springer
Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …