Antifungal mechanisms of a plant defensin MtDef4 are not conserved between the ascomycete fungi Neurospora crassa and Fusarium graminearum

K El‐Mounadi, KT Islam… - Molecular …, 2016 - Wiley Online Library
Defensins play an important role in plant defense against fungal pathogens. The plant
defensin, MtDef4, inhibits growth of the ascomycete fungi, Neurospora crassa and Fusarium …

[HTML][HTML] Structural and functional studies of a phosphatidic acid-binding antifungal plant defensin MtDef4: identification of an RGFRRR motif governing fungal cell …

US Sagaram, K El-Mounadi, GW Buchko, HR Berg… - PloS one, 2013 - journals.plos.org
MtDef4 is a 47-amino acid cysteine-rich evolutionary conserved defensin from a model
legume Medicago truncatula. It is an apoplast-localized plant defense protein that inhibits …

Differential antifungal and calcium channel-blocking activity among structurally related plant defensins

RG Spelbrink, N Dilmac, A Allen, TJ Smith… - Plant …, 2004 - academic.oup.com
Plant defensins are a family of small Cys-rich antifungal proteins that play important roles in
plant defense against invading fungi. Structures of several plant defensins share a Cys …

[HTML][HTML] A novel bi-domain plant defensin MtDef5 with potent broad-spectrum antifungal activity binds to multiple phospholipids and forms oligomers

KT Islam, SLS Velivelli, RH Berg, B Oakley… - Scientific Reports, 2017 - nature.com
Defensins are cysteine-rich cationic antimicrobial peptides contributing to the innate
immunity in plants. A unique gene encoding a highly cationic bi-domain defensin MtDef5 …

Specific domains of plant defensins differentially disrupt colony initiation, cell fusion and calcium homeostasis in Neurospora crassa

A Muñoz, M Chu, PI Marris, US Sagaram… - Molecular …, 2014 - Wiley Online Library
MsDef 1 and MtDef 4 from M edicago spp. are small cysteine‐rich defensins with potent
antifungal activity against a broad range of filamentous fungi. Each defensin has a hallmark …

[HTML][HTML] Structure-Activity Determinants in Antifungal Plant Defensins MsDef1 and MtDef4 with Different Modes of Action against Fusarium graminearum

US Sagaram, R Pandurangi, J Kaur, TJ Smith… - PloS one, 2011 - journals.plos.org
Plant defensins are small cysteine-rich antimicrobial proteins. Their three-dimensional
structures are similar in that they consist of an α-helix and three anti-parallel β-strands …

[HTML][HTML] Hyperpolarisation of mitochondrial membranes is a critical component of the antifungal mechanism of the plant defensin, Ppdef1

K Parisi, JA McKenna, R Lowe, KS Harris, T Shafee… - Journal of Fungi, 2024 - mdpi.com
Plant defensins are a large family of small cationic proteins with diverse functions and
mechanisms of action, most of which assert antifungal activity against a broad spectrum of …

[HTML][HTML] The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae

NL Van Der Weerden, FT Lay, MA Anderson - Journal of Biological …, 2008 - ASBMB
The plant defensin, NaD1, from the flowers of Nicotiana alata displays potent antifungal
activity against a variety of agronomically important filamentous fungi including Fusarium …

[HTML][HTML] Modes of Action of a Bi-domain Plant Defensin MtDef5 Against a Bacterial Pathogen Xanthomonas campestris

SLS Velivelli, KT Islam, E Hobson… - Frontiers in Microbiology, 2018 - frontiersin.org
Defensins are small cysteine-rich endogenous host defense peptides expressed in all
higher plants. They are thought to be important players in the defense arsenal of plants …

[HTML][HTML] Antifungal plant defensins: mechanisms of action and production

K Vriens, BPA Cammue, K Thevissen - Molecules, 2014 - mdpi.com
Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …