A comprehensive review and update on the pathogenesis of inflammatory bowel disease

Q Guan - Journal of immunology research, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …

An overview of the innate and adaptive immune system in inflammatory bowel disease

MC Choy, K Visvanathan… - Inflammatory bowel …, 2017 - academic.oup.com
Inflammatory bowel diseases (IBDs) are thought to develop as a result of complex
interactions between host genetics, the immune system and the environment including the …

Immune aspects of the pathogenesis of inflammatory bowel disease

T Hisamatsu, T Kanai, Y Mikami, K Yoneno… - Pharmacology & …, 2013 - Elsevier
Although the precise etiologies of inflammatory bowel disease (IBD)(ulcerative colitis and
Crohn's disease) remain obscure, several reports have indicated that dysfunction of the …

[HTML][HTML] Immunopathology of inflammatory bowel disease

KL Wallace, LB Zheng, Y Kanazawa… - World journal of …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) results from a complex series of interactions between
susceptibility genes, the environment, and the immune system. The host microbiome, as well …

Inflammatory bowel disease: exploring gut pathophysiology for novel therapeutic targets

V Yadav, F Varum, R Bravo, E Furrer, D Bojic… - Translational …, 2016 - Elsevier
Ulcerative colitis and Crohn's disease are the 2 major phenotypes of inflammatory bowel
disease (IBD), which are influenced by a complex interplay of immunological and genetic …

New frontiers in genetics, gut microbiota, and immunity: a rosetta stone for the pathogenesis of inflammatory bowel disease

M Zhou, J He, Y Shen, C Zhang… - BioMed research …, 2017 - Wiley Online Library
Inflammatory bowel disease (IBD), which encompasses ulcerative colitis (UC) and Crohn's
disease (CD), is a complicated, uncontrolled, and multifactorial disorder characterized by …

Pathogenesis of inflammatory bowel disease and recent advances in biologic therapies

DH Kim, JH Cheon - Immune network, 2017 - synapse.koreamed.org
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …

Pathophysiology of inflammatory bowel diseases

JT Chang - New England Journal of Medicine, 2020 - Mass Medical Soc
Pathophysiology of Inflammatory Bowel Diseases Research on IBDs has identified disrupted
immune responses in the gastrointestinal mucosa and putative disruptions in the gut …

Cytokine networks and T-cell subsets in inflammatory bowel diseases

ML Chen, MS Sundrud - Inflammatory bowel diseases, 2016 - academic.oup.com
Pathogenesis of the inflammatory bowel diseases (IBDs), such as ulcerative colitis (UC) and
Crohn's disease (CD), involve proinflammatory changes within the microbiota, chronic …