Natural history of inoperable hepatocellular carcinoma: estrogen receptors' status in the tumor is the strongest prognostic factor for survival

E Villa, A Moles, I Ferretti, P Buttafoco, A Grottola… - Hepatology, 2000 - Elsevier
Clinical course in hepatocellular carcinoma may be very different. We prospectively
evaluated 96 patients with hepatocellular carcinoma unsuitable for radical therapy to …

Estrogen receptor classification for hepatocellular carcinoma: comparison with clinical staging systems

E Villa, A Colantoni, C Cammà, A Grottola… - Journal of clinical …, 2003 - ascopubs.org
Purpose: Several scoring systems to evaluate patients with hepatocellular carcinoma (HCC)
exist. A good scoring system should provide information on prognosis and guide therapeutic …

Unresectable hepatocellular carcinoma: a prospective controlled trial with tamoxifen

F Farinati, M Salvagnini, N De Maria, A Fornasiero… - Journal of …, 1990 - Elsevier
The liver is an estrogen responsive organ. Clinically, estrogens may play a role in the
induction of liver tumors and, experimentally, estrogens are involved in the control of …

Variant liver estrogen receptor transcripts already occur at an early stage of chronic liver disease

E Villa, A Dugani, A Moles, L Camellini, A Grottola… - Hepatology, 1998 - journals.lww.com
Variant estrogen receptors may be found in hepatocellular carcinoma and may influence its
natural history. Because it is not known whether their occurrence is an early or a late event …

A new prognostic classification for predicting survival in patients with hepatocellular carcinoma

S Chevret, JC Trinchet, D Mathieu, A Abou Rached… - Journal of …, 1999 - Elsevier
Background/Aims: In patients with hepatocellular carcinoma, prediction of survival is difficult.
The aim of this prospective study was to provide a simple classification for predicting survival …

The clinical and pathogenetic significance of estrogen receptor‐β expression in chronic liver diseases and liver carcinoma

M Iavarone, P Lampertico, C Seletti… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Estrogen receptor‐α (ERα) is variably expressed in hepatocellular
carcinoma (HCC) and is believed to be correlated with prognosis and survival. Recently …

Hepatocellular carcinoma in the United States: prognostic features, treatment outcome, and survival

KE Stuart, AJ Anand, RL Jenkins - … International Journal of the …, 1996 - Wiley Online Library
BACKGROUND The purpose of this study was to investigate prognostic factors at
presentation and the survival of North American patients with hepatocellular carcinoma …

Prognostic significance of pathologic features of hepatocellular carcinoma a multivariate analysis of 278 patients

IOL Ng, ECS Lai, ST Fan, MMT Ng, MKP So - Cancer, 1995 - Wiley Online Library
Background. In patients with hepatocellular carcinoma, surgical resection may offer a
chance of cure. However, tumor recurrence is not infrequent after resection. Methods. To …

Natural history of untreated primary hepatocellular carcinoma: a retrospective study of 157 patients

A Pawarode, N Voravud, V Sriuranpong… - American journal of …, 1998 - journals.lww.com
Primary hepatocellular carcinoma (HCC) is a common malignancy with a dismal prognosis;
new modalities of treatment as alternatives to surgery have been developed for …

Prognosis of unresectable hepatocellular carcinoma: an evaluation based on multivariate analysis of 90 cases

Y Akashi, C Koreeda, S Enomoto, S Uchiyama… - Hepatology, 1991 - journals.lww.com
A multivariate analysis of data from 90 patients with unresectable hepatocellular carcinoma
was performed using Cox's regression model to identify factors possibly affecting their …