Platelet biology of the rapidly failing lung

AV Washington, O Esponda… - British journal of …, 2020 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is characterized by a rapid‐onset respiratory
failure with a mortality rate of approximately 40%. This physiologic inflammatory process is …

Platelets in the pathogenesis of acute respiratory distress syndrome

H Yadav, DJ Kor - … Journal of Physiology-Lung Cellular and …, 2015 - journals.physiology.org
Platelets have an emerging and incompletely understood role in a myriad of host immune
responses, extending their role well beyond regulating thrombosis. Acute respiratory …

Amicus or adversary revisited: platelets in acute lung injury and acute respiratory distress syndrome

EA Middleton, MT Rondina, H Schwertz… - American journal of …, 2018 - atsjournals.org
Platelets are essential cellular effectors of hemostasis and contribute to disease as
circulating effectors of pathologic thrombosis. These are their most widely known biologic …

Amicus or adversary: platelets in lung biology, acute injury, and inflammation

FA Bozza, AM Shah, AS Weyrich… - American journal of …, 2009 - atsjournals.org
Platelets are the chief effector cells in hemostasis and have additional major functions in
inflammation, vascular integrity, and tissue repair. Platelets and the lungs have interrelated …

Platelets in lung biology

AS Weyrich, GA Zimmerman - Annual review of physiology, 2013 - annualreviews.org
Platelets and the lungs have an intimate relationship. Platelets are anucleate mammalian
blood cells that continuously circulate through pulmonary vessels and that have major …

Platelets in pulmonary immune responses and inflammatory lung diseases

EA Middleton, AS Weyrich… - Physiological …, 2016 - journals.physiology.org
Platelets are essential for physiological hemostasis and are central in pathological
thrombosis. These are their traditional and best known activities in health and disease. In …

The role of platelets in the adult respiratory distress syndrome: culprits or bystanders?

JE Heffner, SA Sahn, JE Repine - American Review of Respiratory …, 1987 - atsjournals.org
The Role of Platelets in the Adult Respiratory Distress Syndrome Page 1 The Role of Platelets
in the Adult Respiratory Distress Syndrome Culprits or Bystanders? JOHN E. HEFFNER …

[HTML][HTML] The role of platelets in acute lung injury (ALI)

A Zarbock, K Ley - Frontiers in bioscience: a journal and virtual …, 2009 - ncbi.nlm.nih.gov
Acute lung injury (ALI) is a common syndrome associated with a high mortality rate. Better
understanding of the pathophysiology of acute lung injury and progress in supportive care …

Endothelium–platelet interactions in inflammatory lung disease

A Tabuchi, WM Kuebler - Vascular pharmacology, 2008 - Elsevier
In addition to their established role in hemostasis, recent studies have identified platelets as
key regulators of inflammatory reactions. Upon activation, platelets interact with both …

Platelets: a potential role in chronic respiratory diseases?

M Chebbo, C Duez, MC Alessi… - European Respiratory …, 2021 - Eur Respiratory Soc
Platelets are small anucleate cells known for their role in haemostasis and thrombosis. In
recent years, an increasing number of observations have suggested that platelets are also …