A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy

NB Davis, CW Ryan, WM Stadler… - BJU …, 2005 - Wiley Online Library
OBJECTIVE To determine the prostate‐specific antigen (PSA) response and time to PSA or
radiographic progression in men with prostate cancer refractory to bicalutamide and/or …

Nilutamide: an antiandrogen for the treatment of prostate cancer

EJ Dole, MT Holdsworth - Annals of Pharmacotherapy, 1997 - journals.sagepub.com
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and adverse effects of
nilutamide and to compare this agent with the currently marketed nonsteroidal …

Nilutamide: possible utility as a second-line hormonal agent

A Desai, WM Stadler, NJ Vogelzang - Urology, 2001 - Elsevier
Objectives. To study the ability of nilutamide to induce prostate-specific antigen (PSA)
responses in patients with hormone-resistant prostate cancer who had been exposed to …

Bicalutamide and flutamide, each in combination with luteinizing hormone‐releasing hormone analogs, in advanced prostate cancer: exploratory analysis of impact of …

MS Soloway, PF Schellhammer, R Sharifi… - The Prostate …, 2000 - Wiley Online Library
Objectives: We performed an exploratory analysis to determine whether there was a
difference between two antiandrogen‐plus‐luteinizing hormone‐releasing hormone …

Bicalutamide for advanced prostate cancer: the natural versus treated history of disease.

HI Scher, C Liebertz, WK Kelly, M Mazumdar… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE To determine the therapeutic effects of bicalutamide 200 mg in patients with
prostate cancers of different hormone sensitivities. METHODS Patients with progressive …

High-dose bicalutamide monotherapy for the treatment of prostate cancer

GRP Blackledge - Urology, 1996 - Elsevier
Objectives. Bicalutamide is a nonsteroidal competitive inhibitor of androgens at the
androgen receptor. The level of blockade that can be achieved is dependent on the relative …

Efficacy of nilutamide as secondary hormonal therapy in androgen‐independent prostate cancer

M Nakabayashi, MM Regan, D Lifsey… - BJU …, 2005 - Wiley Online Library
OBJECTIVE To evaluate the activity of nilutamide as secondary hormonal therapy in patients
with androgen‐independent prostate cancer (AIPC), as treatment options are limited for …

Tolerability of antiandrogens in the treatment of prostate cancer

RO Fourcade, D McLeod - UroOncology, 2004 - Taylor & Francis
This article presents and discusses data on the tolerability of the antiandrogens, both
steroidal (cyproterone acetate; CPA) and non-steroidal (bicalutamide, flutamide, nilutamide) …

Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails

W Kassouf, S Tanguay, AG Aprikian - The Journal of urology, 2003 - auajournals.org
Purpose: We investigate the prostate specific antigen (PSA) response rate with nilutamide
as a second line hormonal agent in patients with advanced prostate cancer in whom …

Clinical outcome of maximum androgen blockade using flutamide as second‐line hormonal therapy for hormone‐refractory prostate cancer

H Miyake, I Hara, H Eto - BJU international, 2005 - Wiley Online Library
OBJECTIVES To investigate the efficacy of maximum androgen blockade (MAB) using
flutamide as second‐line hormonal therapy for advanced hormone‐refractory prostate …