A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy
OBJECTIVE To determine the prostate‐specific antigen (PSA) response and time to PSA or
radiographic progression in men with prostate cancer refractory to bicalutamide and/or …
radiographic progression in men with prostate cancer refractory to bicalutamide and/or …
Nilutamide: an antiandrogen for the treatment of prostate cancer
EJ Dole, MT Holdsworth - Annals of Pharmacotherapy, 1997 - journals.sagepub.com
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and adverse effects of
nilutamide and to compare this agent with the currently marketed nonsteroidal …
nilutamide and to compare this agent with the currently marketed nonsteroidal …
Nilutamide: possible utility as a second-line hormonal agent
A Desai, WM Stadler, NJ Vogelzang - Urology, 2001 - Elsevier
Objectives. To study the ability of nilutamide to induce prostate-specific antigen (PSA)
responses in patients with hormone-resistant prostate cancer who had been exposed to …
responses in patients with hormone-resistant prostate cancer who had been exposed to …
Bicalutamide and flutamide, each in combination with luteinizing hormone‐releasing hormone analogs, in advanced prostate cancer: exploratory analysis of impact of …
MS Soloway, PF Schellhammer, R Sharifi… - The Prostate …, 2000 - Wiley Online Library
Objectives: We performed an exploratory analysis to determine whether there was a
difference between two antiandrogen‐plus‐luteinizing hormone‐releasing hormone …
difference between two antiandrogen‐plus‐luteinizing hormone‐releasing hormone …
Bicalutamide for advanced prostate cancer: the natural versus treated history of disease.
HI Scher, C Liebertz, WK Kelly, M Mazumdar… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE To determine the therapeutic effects of bicalutamide 200 mg in patients with
prostate cancers of different hormone sensitivities. METHODS Patients with progressive …
prostate cancers of different hormone sensitivities. METHODS Patients with progressive …
High-dose bicalutamide monotherapy for the treatment of prostate cancer
GRP Blackledge - Urology, 1996 - Elsevier
Objectives. Bicalutamide is a nonsteroidal competitive inhibitor of androgens at the
androgen receptor. The level of blockade that can be achieved is dependent on the relative …
androgen receptor. The level of blockade that can be achieved is dependent on the relative …
Efficacy of nilutamide as secondary hormonal therapy in androgen‐independent prostate cancer
M Nakabayashi, MM Regan, D Lifsey… - BJU …, 2005 - Wiley Online Library
OBJECTIVE To evaluate the activity of nilutamide as secondary hormonal therapy in patients
with androgen‐independent prostate cancer (AIPC), as treatment options are limited for …
with androgen‐independent prostate cancer (AIPC), as treatment options are limited for …
Tolerability of antiandrogens in the treatment of prostate cancer
RO Fourcade, D McLeod - UroOncology, 2004 - Taylor & Francis
This article presents and discusses data on the tolerability of the antiandrogens, both
steroidal (cyproterone acetate; CPA) and non-steroidal (bicalutamide, flutamide, nilutamide) …
steroidal (cyproterone acetate; CPA) and non-steroidal (bicalutamide, flutamide, nilutamide) …
Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails
W Kassouf, S Tanguay, AG Aprikian - The Journal of urology, 2003 - auajournals.org
Purpose: We investigate the prostate specific antigen (PSA) response rate with nilutamide
as a second line hormonal agent in patients with advanced prostate cancer in whom …
as a second line hormonal agent in patients with advanced prostate cancer in whom …
Clinical outcome of maximum androgen blockade using flutamide as second‐line hormonal therapy for hormone‐refractory prostate cancer
H Miyake, I Hara, H Eto - BJU international, 2005 - Wiley Online Library
OBJECTIVES To investigate the efficacy of maximum androgen blockade (MAB) using
flutamide as second‐line hormonal therapy for advanced hormone‐refractory prostate …
flutamide as second‐line hormonal therapy for advanced hormone‐refractory prostate …