Atrial fibrillation predisposes to left atrial thrombus formation and carries a sixfold increased
risk for stroke. Antithrombotic therapies are the mainstay for stroke prevention. The National …

Atrial fibrillation is associated with a sixfold increased risk for stroke. More than a dozen
published randomized trials of anticoagulants or antiplatelet agents for stroke prevention …

Purpose: To characterize the efficacy and safety of anticoagulants and antiplatelet agents for
prevention of stroke in patients with atrial fibrillation. Data Sources: Randomized trials …

Background We aimed to identify different stroke prevention treatments for atrial fibrillation
assessed in randomized controlled trials and to compare them within a single evidence …

BACKGROUNDAtrial fibrillation in the absence of rheumatic valvular disease is associated
with a fivefold to sevenfold increased risk of ischemic stroke. METHODS AND MAIN …

Background: The Stroke Prevention in Atrial Fibrillation II study compared warfarin vs aspirin
for stroke prevention in atrial fibrillation. Bleeding complications importantly detracted from …

OBJECTIVE: Appropriate use of drugs to prevent thromboembolism in patients with atrial
fibrillation (AF) involves comparing the patient's risk of stroke and risk of hemorrhage. This …

Background and Purpose—Nonvalvular atrial fibrillation (AF) is a strong, independent risk
factor for stroke, but the absolute rate of stroke varies widely among AF patients, importantly …

Atrial fibrillation (AF) is common, and it increases the risk of stroke. Placebo-controlled trials
consistently showed that warfarin reduces the risk of stroke by two thirds, and a meta …

ContextWarfarin has been shown to be highly efficacious for preventing thromboembolism in
atrial fibrillation in randomized trials, but its effectiveness and safety in clinical practice is …