Leukemia lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after …

J Mattsson, M Uzunel, L Tammik, J Aschan, O Ringden - Leukemia, 2001 - nature.com
One of the major complications after allogeneic stem cell transplantation (SCT) in patients
with malignant disease is a high frequency of relapse. We have prospectively analyzed the …

[HTML][HTML] Mixed T lymphocyte chimerism after allogeneic hematopoietic transplantation is predictive for relapse of acute myeloid leukemia and myelodysplastic …

HC Lee, RM Saliba, G Rondon, J Chen… - Biology of Blood and …, 2015 - Elsevier
Chimerism testing after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in
patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) …

Characterization of lineage‐specific chimaerism in patients with acute leukaemia and myelodysplastic syndrome after allogeneic stem cell transplantation before and …

P Bader, K Stoll, S Huber, A Geiselhart… - British journal of …, 2000 - Wiley Online Library
Recently, we have shown that patients with acute leukaemias and myelodysplastic
syndromes (MDS), who showed increasing mixed chimaerism (MC) upon serial PCR …

Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia

C Huisman, RA De Weger, L De Vries… - Bone marrow …, 2007 - nature.com
The role of chimerism analysis as a prognostic indicator of relapse after hematopoietic stem
cell transplantation (SCT) is controversial. We monitored chimerism status by short tandem …

Reliable quantification of hematopoietic chimerism after allogeneic transplantation for acute leukemia using amplification by real-time PCR of null alleles and insertion …

A Jimenez-Velasco, M Barrios, J Roman-Gomez… - Leukemia, 2005 - nature.com
Increasing mixed chimerism (MC) after allogeneic stem cell transplantation (SCT) has been
associated with a high risk of relapse in acute leukemia. We evaluated a new method for …

Chimerism status is a useful predictor of relapse after allogeneic stem cell transplantation for acute leukemia

M Barrios, A Jiménez-Velasco, J Román-Gómez… - …, 2003 - haematologica.org
BACKGROUND AND OBJECTIVES: The role of hematopoietic chimerism after allogeneic
stem cell transplantation (SCT) for acute leukemia remains controversial. We studied the …

[HTML][HTML] Monitoring of donor chimerism in sorted CD34+ peripheral blood cells allows the sensitive detection of imminent relapse after allogeneic stem cell …

M Bornhäuser, U Oelschlaegel, U Platzbecker… - …, 2009 - ncbi.nlm.nih.gov
Abstract Analysis of donor chimerism is an important diagnostic tool to assess the risk of
relapse after allogeneic stem cell transplantation, especially in patients lacking a specific …

[HTML][HTML] Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia

B Wiedemann, E Klyuchnikov, N Kröger… - Experimental …, 2010 - Elsevier
OBJECTIVE: Chimerism is well-established for surveillance of acute myeloid leukemia
(AML) patients after allogeneic hematopoietic stem cell transplantation (HSCT), but …

Detection of relapse by sequential monitoring of chimerism in circulating CD34+ cells.

T Ch, K Lutterbeck, U Oelschlägel, M Kiehl… - Annals of …, 2002 - europepmc.org
Relapse of the underlying malignant disease represents one of the major causes of
treatment failure in patients treated with stem cell transplantation, especially in patients with …

Lineage-specific early complete donor chimerism and risk of relapse after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

H Lindahl, S Vonlanthen, D Valentini… - Bone Marrow …, 2022 - nature.com
Recipient–donor chimerism is routinely analyzed after allogeneic hematopoietic stem cell
transplantation (HSCT) to monitor engraftment and graft rejection. For malignancies …