The current progressive aging of the population is resulting in a continuous increase in the
incidence of gliomas in elderly people, especially the most frequent subtype, glioblastoma …

Abstract Purpose of Review The incidence of glioblastoma multiforme (GBM) increases with
age; more than half of newly diagnosed patients are older than 65 years. Due to age …

Introduction Glioblastoma multiforme (GBM) has a peak incidence in patients older than 65
years. The aim of the present study is to evaluate the impact of surgical strategy on short-and …

Objective To evaluate the role and possible complications of tumor resection in the
management of glioblastoma (GBM) in a series of patients 80 years of age and older with …

Aim: The optimal treatment for elderly glioblastoma patients is unclear. We conducted a
retrospective review of the California Cancer Registry to examine treatment patterns and …

Introduction: Elderly patients with glioblastoma multiforme (GBM) are frequently excluded
from cancer therapy trials, treated suboptimally or not treated at all. The average survival in …

Treatment of older patients with glioblastoma must take into account reduced treatment
benefits and increased treatment-related toxicity, as this group of frail patients has a …

Background Frailty is an emerging means of assessing overall health status and guiding
management for geriatric patients. Frailty is associated with outcomes for many surgical …

Glioblastoma, a WHO grade IV astrocytoma, is the most common primary malignant brain
tumor in adults. It is characterized by molecular heterogeneity and aggressive behavior …

Background Glioblastoma predominantly occurs in the 6th and 7th decades of life. The
optimal treatment paradigm for elderly patients is not well established. We sampled current …