Pramipexole (PPX) is a common drug for the treatment of Parkinson's disease. However, the
mechanism allows PPX in the progression of Parkinson's disease remains largely unknown …

Background Parkinson's disease is a common neurodegenerative problem. Pramipexole
(PPX) plays protective role in Parkinson's disease. Nevertheless, the mechanism of PPX in …

Neuroinflammation is the key factor associated with the progression of Parkinson's disease
(PD). Pramipexole (PPX) has anti-inflammatory and antioxidant properties. This study …

Baicalein, a major bioactive flavone constituent isolated from Scutellaria baicalensis Georgi,
has neuroprotective properties in several neurological disorders. Many studies suggest that …

In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

Background: At present, symptomatic treatment may improve the life quality of Parkinson's
disease (PD) patients to a certain extent but cannot completely cure PD. Therefore, it is …

Our recent study demonstrated that pinocembrin (PB), the most abundant flavonoid in
propolis, has neuroprotective effect against 1-methyl-4-phenylpyridinium (MPP+)-induced …

Miltirone is a phenanthrene-quinone derived from Salvia miltiorrhiza Bunge with anti-
inflammatory and anti-oxidant effects. Our study aimed to explore the protective effect of …

Danshensu (DSS) and tetramethylpyrazine (TMP) are active ingredients of Salvia
miltiorrhiza Bge. and Ligusticum chuanxiong Hort that are widely used in oriental medicine …

Parkinson's disease (PD) is characterized by the selective death of dopaminergic neurons.
To avoid inconvenience of frequent administration caused by short half life and recurrence …