To assess the role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in the
development of fatty liver, we have used LDLr−/− mice as an animal model of high-fat, high …

Abstract Monocyte chemoattractant protein-1 (MCP-1, Ccl2) expression is increased in livers
of patients with nonalcoholic steatohepatitis and in murine models of steatohepatitis. Several …

We describe the effect of MCP-1 deficiency in mice rendered hyperlipemic by the
concomitant ablation of the LDL receptor. The MCP-1−/− LDLr−/− mice in comparison with …

Non-alcoholic fatty liver disease (NAFLD) is strongly associated with obesity and the
metabolic syndrome. It encompasses a clinico-pathologic spectrum of conditions ranging …

The importance of chemokines in alcoholic liver injury has been implicated. The role of the
chemokine, monocyte chemoattractant protein‐1 (MCP‐1), elevated in patients with …

BACKGROUND & AIMS: Monocyte chemoattractant protein 1 (MCP-1) is a potent monocyte/
macrophage chemoattractant expressed by fat-storing cells (FSCs) in rat models of liver …

Aims/hypothesis Monocyte chemoattractant protein-1 (MCP-1)/chemokine (CC motif) ligand
(CCL) 2 (CCL2) secreted from white adipose tissue (WAT) in obesity has been reported to …

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other
tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) …

OBJECTIVE—Monocyte chemoattractant protein-1 (MCP-1), a CC-motif chemokine, has
been proposed to play critical roles in insulin resistance and recruitment of monocytes into …

Monocyte adherence to the endothelium and subsequent migration into the subendothelial
space are important early events in atherogenesis. Monocyte chemotactic protein-1 (MCP-1) …