Intravenous anesthetic ketamine attenuates complete Freund's adjuvant-induced arthritis in rats via modulation of MAPKs/NF-κB

H Lin, Z Wang, J Shen, J Xu, H Li - Inflammation Research, 2019 - Springer
Background The current study was intended to investigate the effect of ketamine (KET) on
complete Freund's adjuvant (CFA)-induced arthritis in rats. Methods The CFA was …

Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases

KC Chuang, YW Lai, CH Ko, CC Yen, HL Chen… - Life sciences, 2023 - Elsevier
Aims Rheumatoid arthritis (RA) is a chronic autoimmune disease. Its pathological features
are synovial inflammation, bone erosion, and joint structural damages. Our previous studies …

[HTML][HTML] Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model

W Lu, L Wang, C Wo, J Yao - Molecular Medicine …, 2016 - spandidos-publications.com
The aim of the present study was to investigate the efficacy of ketamine in attenuating
osteoarthritis (OA) and modulating the expression of inflammatory mediators. A rabbit OA …

Protective effect of apigenin on Freund's complete adjuvant-induced arthritis in rats via inhibiting P2X7/NF-κB pathway

X Chang, H He, L Zhu, J Gao, T Wei, Z Ma… - Chemico-Biological …, 2015 - Elsevier
To evaluate the effect of apigenin (AP) on arthritis in rats stimulated by Freund's complete
adjuvant (FCA) was the main purpose of the investigation. Arthritis model was established …

Inhibition of glycolysis ameliorate arthritis in adjuvant arthritis rats by inhibiting synoviocyte activation through AMPK/NF-кB pathway

Y Wang, H Xian, J Qi, F Wei, X Cheng, S Li… - Inflammation …, 2020 - Springer
Objective This study aimed to evaluate glycolysis inhibitor which can effectively ameliorate
arthritis by inhibiting synoviocyte activation through AMPK/NF-кB pathway in AA rats …

Trikatu, an herbal compound ameliorates rheumatoid arthritis by the suppression of inflammatory immune responses in rats with adjuvant-induced arthritis and on …

HM Doss, R Ganesan, M Rasool - Chemico-biological interactions, 2016 - Elsevier
The present study was designed to investigate the potential therapeutic effect of trikatu, an
herbal compound and its underlying molecular mechanism in rats with adjuvant-induced …

Effect of umbelliferone on adjuvant-induced arthritis in rats by MAPK/NF-κB pathway

L Ouyang, Y Dan, Z Shao, S Yang, C Yang… - Drug design …, 2019 - Taylor & Francis
Purpose Umbelliferone (Umb), a member of coumarin family, is found in many plants and is
a promising molecule with potential anti-inflammatory, anti-oxidative, and anti-tumor …

Effects of Naringenin on inflammation in complete freund's adjuvant-induced arthritis by regulating Bax/Bcl-2 balance

L Zhu, J Wang, T Wei, J Gao, H He, X Chang, T Yan - Inflammation, 2015 - Springer
Naringin (COG) is a flavanone with various bioactivities including an expectorant effect,
antitussive effect, and inhibitory effect on asthma and acute lung injury. The aims of the …

Kirenol upregulates nuclear annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats

ZM Wang, SG Zhu, ZW Wu, Y Lu, HZ Fu… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Kirenol is a diterpenoid compound purified
from the Chinese Herba Siegesbeckiae. Siegesbeckiae has been employed for the …

Therapeutic effect of penta-acetyl geniposide on adjuvant-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting NF-κB signal pathway

L Cai, C Li, W Tang, M Liu, W Chen, Y Qiu, R Li - Inflammation, 2018 - Springer
Previous studies demonstrated that penta-acetyl geniposide ((Ac) 5 GP, an acetylated
derivative of geniposide) exhibited better pharmacological functions than geniposide. This …