Leveraging “raw materials” as building blocks and bioactive signals in regenerative medicine

AN Renth, MS Detamore - Tissue Engineering Part B: Reviews, 2012 - liebertpub.com
Components found within the extracellular matrix (ECM) have emerged as an essential
subset of biomaterials for tissue engineering scaffolds. Collagen, glycosaminoglycans …

Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling

R Londono, SF Badylak - Annals of biomedical engineering, 2015 - Springer
Successful regenerative medicine strategies for functional tissue reconstruction include the
in situ placement of acellular materials composed of the extracellular matrix (ECM) or …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

A review of decellularized extracellular matrix biomaterials for regenerative engineering applications

DE Heath - Regenerative Engineering and Translational Medicine, 2019 - Springer
Biomaterials are a cornerstone technology of the biomedical device, tissue engineering, and
regenerative medicine industries. While traditional biomaterials are fully defined synthetics …

[HTML][HTML] Decellularized extracellular matrix biomaterials for regenerative therapies: Advances, challenges and clinical prospects

AA Golebiowska, JT Intravaia, VM Sathe, SG Kumbar… - Bioactive Materials, 2024 - Elsevier
Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

Potential synergistic effects of stem cells and extracellular matrix scaffolds

L Gaffney, EA Wrona, DO Freytes - ACS Biomaterials Science & …, 2017 - ACS Publications
In recent years, extracellular matrix (ECM)-derived biomaterials have been used as scaffolds
to help regenerate diseased or damaged tissues. These biomaterials are prepared by …

Extracellular matrix-based biomaterial scaffolds and the host response

JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Natural and synthetic scaffolds

PS Wolfe, SA Sell, GL Bowlin - Tissue Engineering: From Lab to Clinic, 2010 - Springer
Tissue engineering is an interdisciplinary field aimed at the application of the principles and
methods of engineering and life sciences toward the fundamental understanding of structure …

Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …