Amyloid β-protein (Aβ) is linked to neuronal injury and death in Alzheimer's disease (AD). Of
particular relevance for elucidating the role of Aβ in AD is new evidence that oligomeric …

Understanding the structural and assembly dynamics of the amyloid β-protein (Aβ) has
direct relevance to the development of therapeutic agents for Alzheimer disease. To …

Assembly of monomeric amyloid β-protein (Aβ) into oligomeric structures is an important
pathogenetic feature of Alzheimer's disease. The oligomer size distributions of aggregate …

Assembly of the amyloid β-protein (Aβ) into neurotoxic oligomers and fibrils is a seminal
event in Alzheimer's disease. Understanding the earliest phases of Aβ assembly, including …

Increasing evidence suggests that soluble aggregates of amyloid-β (Aβ) initiate the
neurotoxicity that eventually leads to dementia in Alzheimer's disease. Knowledge on …

We examined the effects of co‐incubating nine different Aβ peptide fragments with full‐
length Aβ1–40 (Aβ40) on protein aggregation. Six fragments enhanced aggregation of Aβ40 …

Evidence suggests that oligomers of the 42-residue form of the amyloid β-protein (Aβ), Aβ42,
play a critical role in the etiology of Alzheimer's disease (AD). Here we use high resolution …

The assembly of proteins into amyloid fibrils, a phenomenon central to several currently
incurable human diseases, is a process of high specificity that commonly tolerates only a …

The amyloid β peptide (Aβ), composed of 40 or 42 amino acids, is a critical component in the
etiology of the neurodegenerative Alzheimer disease. Aβ is prone to aggregate and forms …

Recent research has focused on soluble oligomeric assemblies of the 42 amino acid isoform
of the amyloid‐beta peptide (Aβ42) as the proximal cause of neuronal injury, synaptic loss …