BACKGROUND & AIMS: Acute inflammation of the intestine is associated with
transepithelial migration of polymorphonuclear leukocytes (PMNs) and epithelial wounds …

Neutrophil-mediated injury to gut epithelium may lead to disruption of the epithelial barrier
function with consequent organ dysfunction, but the mechanisms of this are incompletely …

Active migration of polymorphonuclear leukocytes (PMN) through the intestinal crypt
epithelium is a hallmark of inflammatory bowel disease and correlates with patient …

Neutrophils are the most abundant leukocyte population in the human circulatory system
and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in …

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of gastrointestinal
inflammation, with significant implications for host defense, injury and repair. However …

Recruitment of polymorphonuclear leucocytes (PMN) across the intestinal epithelium is
dependent on specific adhesion molecules and chemoattractants diffusing from the …

During inflammatory bowel diseases, commitment of extravased polymorphonuclear
leucocytes (PMN) to apoptosis is required for the resolution of inflammation. To investigate …

Abstract Neutrophil [polymorphonuclear leukocyte (PMN)] transepithelial migration (TEM) is
a hallmark of inflammatory mucosal disorders. PMN TEM is associated with epithelial injury; …

Neutrophil (PMN) mobilization to sites of insult is critical for host defense and requires
transendothelial migration (TEM). TEM involves several well-studied sequential adhesive …

The migration of polymorphonuclear leukocytes (PMNs) across the intestinal epithelium is a
histopathological hallmark of many mucosal inflammatory diseases including inflammatory …