Advances and declining costs in sequencing technology will result in increasing number of
studies with individual sequence data linked to phenotypic information, which has been …

The sequencing of the human genome and technological advances in DNA sequencing
have led to a revolution with respect to DNA sequencing and its potential to diagnose …

The introduction of new sequencing technologies whole-genome sequencing (WGS) and
whole-exome sequencing (WES) that are much less finely targeted than previous genetic …

Background. Today, new and powerful sequencing technology is being used in biomedical
research. In parallel, an intense ethical debate has arisen regarding the handling of the …

Efforts are underway to harmonise the return of individual results and incidental findings
from whole genome sequencing (WGS) across research contexts and countries. We …

Advances in genomic technology make possible the large-scale collection of genomic data
for research purposes. Many international initiatives seek to collect genomic data on large …

Research on the use of genome and exome sequencing for diagnosis, identification of
potential therapies, precision prescribing of pharmaceuticals, and identification of disease …

Rapid technological advances are decreasing DNA sequencing costs and making it
practical to undertake complete human genome sequencing on a large scale for the first …

The use of genome-wide association studies (GWAS) in medical research and the increased
ability to share data give a new twist to some of the perennial ethical issues associated with …

To fully appreciate genetics, one must understand the link between genotype (DNA
sequence) and phenotype (observable characteristics). Advances in high‐throughput …