An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

New therapeutics for ulcerative colitis

RP Hirten, BE Sands - Annual review of medicine, 2021 - annualreviews.org
Ulcerative colitis (UC) is a relapsing and remitting inflammatory disease of the colon with a
variable course. Despite advances in treatment, only approximately 40% of patients achieve …

Emerging therapies for ulcerative colitis: updates from recent clinical trials

T AlAmeel, A AlMutairdi… - Clinical and Experimental …, 2023 - Taylor & Francis
Ulcerative colitis (UC) is a chronic and progressive inflammatory disorder that affects the
colon. The advent of advanced therapies such as biologic agents and small molecules has …

Emerging therapies for ulcerative colitis

J Hanzel, MS Hulshoff, J Grootjans… - Expert Review of …, 2022 - Taylor & Francis
Introduction Despite advances in the medical management of ulcerative colitis (UC), a
subgroup of patients does not respond to currently available therapies. A number of novel …

Ulcerative colitis: current and emerging treatment strategies

M Kayal, S Shah - Journal of clinical medicine, 2019 - mdpi.com
Historically, medical therapy for ulcerative colitis (UC) was limited to corticosteroids.
Excitingly, over the past just 1–2 decades, the options for medical therapy have expanded …

Breaking the therapeutic ceiling in drug development in ulcerative colitis

D Alsoud, B Verstockt, C Fiocchi… - The lancet …, 2021 - thelancet.com
Increased knowledge of the intricate pathogenesis of ulcerative colitis has triggered an
advance in drug development during the past two decades, resulting in the advent of several …

Treatment algorithm for mild and moderate-to-severe ulcerative colitis: an update

E Burri, MH Maillard, AM Schoepfer, F Seibold… - Digestion, 2020 - karger.com
Background: Patient care in ulcerative colitis (UC) remains challenging despite an array of
established treatment options and emerging new therapies. The management of UC therapy …

Therapeutic strategies for the management of ulcerative colitis

SC Ng, MA Kamm - Inflammatory bowel diseases, 2009 - academic.oup.com
Induction and maintenance of remission, mucosal healing, the avoidance of surgical
intervention, and decreasing the likelihood of cancer developing are the primary therapeutic …

Small molecule oral targeted therapies in ulcerative colitis

UN Shivaji, OM Nardone, R Cannatelli… - The Lancet …, 2020 - thelancet.com
The incidence and prevalence of ulcerative colitis are increasing globally. Although the
exact cause and pathogenesis of this disease is unclear, research has led to a better …

New therapeutic avenues in ulcerative colitis: thinking out of the box

J Torres, S Danese, JF Colombel - Gut, 2013 - gut.bmj.com
Ulcerative colitis (UC) is a chronic idiopathic inflammatory disease of the gastrointestinal
tract that affects the mucosal lining of the colon. Recent epidemiological data show that its …