[HTML][HTML] Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy

Y Fan, JJ Moon - Vaccines, 2015 - mdpi.com
Recent studies have demonstrated great therapeutic potential of educating and unleashing
our own immune system for cancer treatment. However, there are still major challenges in …

Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions

J Liu, R Zhang, ZP Xu - Small, 2019 - Wiley Online Library
Cancer immunotherapy is a promising cancer terminator by directing the patient's own
immune system in the fight against this challenging disorder. Despite the monumental …

Nanoparticle systems for cancer vaccine

R Wen, AC Umeano, Y Kou, J Xu, AA Farooqi - Nanomedicine, 2019 - Future Medicine
As effective tools for public health, vaccines prevent disease by priming the body's adaptive
and innate immune responses against an infection. Due to advances in understanding …

Nanoparticle-based immunotherapy for cancer

K Shao, S Singha, X Clemente-Casares, S Tsai… - ACS …, 2015 - ACS Publications
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

Engineered nanoparticles for cancer vaccination and immunotherapy

ME Aikins, C Xu, JJ Moon - Accounts of chemical research, 2020 - ACS Publications
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …

Nanoparticles for immune stimulation against infection, cancer, and autoimmunity

S Singha, K Shao, KK Ellestad, Y Yang, P Santamaria - ACS nano, 2018 - ACS Publications
Vaccination using nanocarrier-based delivery systems has recently emerged as a promising
approach for meeting the continued challenge posed by infectious diseases and cancer. A …

Nanoparticle‐based manipulation of antigen‐presenting cells for cancer immunotherapy

RH Fang, AV Kroll, L Zhang - Small, 2015 - Wiley Online Library
Immunotherapeutic approaches for treating cancer overall have been receiving a
considerable amount of interest due to the recent approval of several clinical formulations …

Dendritic cell-based nanovaccines for cancer immunotherapy

LE Paulis, S Mandal, M Kreutz, CG Figdor - Current opinion in immunology, 2013 - Elsevier
Cancer immunotherapy critically relies on the efficient presentation of tumor antigens to T-
cells to elicit a potent anti-tumor immune response aimed at life-long protection against …

Recent advances in applying nanotechnologies for cancer immunotherapy

R Mahjub, S Jatana, SE Lee, Z Qin, G Pauli… - Journal of controlled …, 2018 - Elsevier
Cancer immunotherapy aimed at boosting cancer-specific immunoresponses to eradicate
tumor cells has evolved as a new treatment modality. Nanoparticles incorporating antigens …

Harnessing designed nanoparticles: Current strategies and future perspectives in cancer immunotherapy

SD Jo, GH Nam, G Kwak, Y Yang, IC Kwon - Nano Today, 2017 - Elsevier
Although cancer immunotherapy, represented by chimeric antigen receptor (CAR) T-cell
therapy and immune checkpoint-blockade therapies, has shown durable outcomes, the …