Presynaptic H3 receptors occur on histaminergic neurones of the CNS (autoreceptors) and
on non‐histaminergic neurones of the central and autonomic nervous system …

The third histamine receptor was discovered in 1983 by a traditional pharmacological
approach, consisting of assessing the inhibitory effect of histamine on its own release from …

The recent cloning and characterization of the human histamine H3 receptor cDNA marked
a significant step toward a greater understanding of the role of this receptor in the central …

We studied several histamine homologues as potential ligands for the histamine H3 receptor
in two binding assays ([125l] iodo-phenpropit and Na [H] methylhistamine binding to rat …

In brain, histamine (HA) is the transmitter of a neuronal system resembling other
monoaminergic systems. It is also present in mast cells from which it may control vascular …

Histamine regulates neurotransmitter release in the central and peripheral nervous systems
through H3 presynaptic receptors. The existence of the histamine H3 receptor was …

Histamine, a ubiquitous cell-to-cell messenger, exerts its numerous actions through
interaction with three pharmacologically distinct receptor subtypes, termed H1, H2 and H3 …

Expression and function of histamine H 4 R in central and peripheral nervous system have
been a matter of controversy for more than a decade. The scientific discussion is often …

Constitutive activity has been mainly recorded for numerous overexpressed and/or mutated
receptors. The histamine H 3 receptor (H 3 R) is a target of choice to study the physiological …

We cloned the full length guinea pig H 3 receptor cDNA using RT-PCR amplification with
primers from the human receptor and templates from brain areas. Evidence was obtained for …