Background Antidepressants are among the most commonly prescribed drugs worldwide.
They are often discontinued, frequently without the knowledge of the prescribing physician. It …

Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …

Withdrawal reactions when coming off antidepressants have long been neglected or
minimised. It took almost two decades after the selective serotonin reuptake inhibitors …

Introduction Evidence is lacking on withdrawal syndrome related to individual
antidepressants and relevant risk factors for severe reactions. Objective To ascertain …

Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

We now recognise that withdrawal symptoms from antidepressants are common, and can be
severe and long-lasting in some people. Many withdrawal symptoms overlap with symptoms …

Background Antidepressant discontinuation symptoms are becoming an increasingly
important part of clinical practice, but the incidence of antidepressant discontinuation …

Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

Discontinuation symptoms are recognised with tricyclic antidepressants, monoamine
oxidase inhibitors, selective serotonin reuptake inhibitors (SSRIs) and miscellaneous …

Sudden or tapered withdrawal from treatment with antidepressants, including monoamine
oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and serotonin selective …